The Story of Successful Drugs and Recent FDA-Approved Molecules

A topical collection in Pharmaceuticals (ISSN 1424-8247). This collection belongs to the section "Medicinal Chemistry".

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1. Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), 4450-208 Porto, Portugal
2. Laboratory of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: medicinal chemistry; organic synthesis; heterocycles; P-glycoprotein; anticancer; antimicrobials; chiral drugs; marine natural products
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Formerly Head, Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium
Interests: heterocycles; medicinal chemistry; green chemistry; microwave-induced synthesis
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PharmaCampus Institute of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität, Corrensstr. 48, 48149 Muenster, Germany
Interests: autodisplay; assay development and inhibitor testing; whole cell biocatalysts for synthesis of drugs and building blocks; directed evolution of enzyme inhibitors and biocatalysts; biosensor development and diagnostic tools
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Topical Collection Information

Dear Colleagues,

Each year, the FDA approves dozens of novel small molecules and biological derivatives as new therapeutic compounds, thus demonstrating the vigor of the pharmaceutical industry and associated research groups. Small molecules are the most represented entities among the approvals, but there are also an increasing number of antibodies and oligonucleotides on the medical market. Interestingly, there is a growing interest in the development of orphan drugs and the treatment of orphan diseases and rare diseases.

We invite readers of this Topical Collection to explore a range of short but comprehensive and updated reviews on drugs attracting particular attention owing to their success and to their compounds being (recently) approved by the FDA.

Dr. Maria Emília De Sousa
Dr. Jean Jacques Vanden Eynde
Prof. Dr. Klaus Kopka
Dr. Annie Mayence
Prof. Dr. Joachim Jose
Prof. Dr. Guangshun Wang
Collection Editors

Manuscript Submission Information

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  • antibody
  • aptamer
  • oligonucleotide
  • orphan disease
  • orphan drug
  • peptide
  • small molecule

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