Special Issue "Pharmacomicrobiomics and Botanicals: Effect of Gut Microbiota on Botanicals"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".

Deadline for manuscript submissions: closed (28 September 2023) | Viewed by 296

Special Issue Editors

National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS, USA
Interests: chromatographic analysis; metabolomics; pharmacokinetic; pharmacomicrobiomics; drug discovery from natural product
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS, USA
Interests: active metabolites; microbial enzymes; drug metabolism; herb–drug interaction; dietary supplements
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA
Interests: natural products chemistry; active metabolites; structure elucidation; dietary supplements

Special Issue Information

Dear Colleagues,

We welcome you to submit your findings on gut microbiota-related botanical research. Botanicals are the major components of different traditional medicines and dietary supplements, but poor knowledge on botanicals’ mechanisms has limited their clinical translation. The gut, the largest digestive organ of the body, harbors trillions of microbes with diversified genera, which are collectively known as the gut microbiota. They greatly influence orally administered botanicals by modulating their phytoconstituents. The newly formed chemicals differ from the parental phytoconstituents concerning their bioavailability, bioactivity, and chemical properties. On the other hand, phytoconstituents of ingested botanicals may affect the gut ecosystem, especially microbial diversity, their populations, and their secretions, which play an enormous role in therapeutic activity and efficacy. Phytoconstituents changed by gut microbiota and their secretion will help to explore the underlying mechanism for botanicals on a deeper level. An understanding of gut microbiota and botanical interaction will provide new insights into precision drug discovery from botanical and generate scientific evidence for its clinical translation.

This Special Issue aims to bring together articles that explore scientific research on all aspects of gut microbiota and botanical interactions, including gut microbiota-based metabolism of botanicals, the in silico prediction of metabolites formed through gut microbiota, pharmacokinetic assessment, the effect of gut microbiota on efficacy, targeted and untargeted metabolomics, gut microbe on the immune system, the effect of botanicals on gut microbial biodiversity and qualitative and quantitative chemical analysis. Papers addressing the pharmacological evaluation of botanicals and their synergistic effect with gut microbes are also welcome.

Dr. Washim Khan
Dr. Islam Husain
Dr. Zulfiqar Ali
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • gut microbiota
  • botanicals
  • biotransformation
  • pharmacokinetic
  • metabolomics
  • pharmacological evaluation

Published Papers

There is no accepted submissions to this special issue at this moment.
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