Special Issue "Molecular Mechanisms of Action of Natural Products in Alleviating Allergic Disease Symptoms"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 296

Special Issue Editor

Faculty of Biology and Biotechnology, University of Warmia and Mazury, 10-719 Olsztyn, Poland
Interests: allergic disease; human immunology; pathways of intercellular communication and antigen presentation and induction of immune tolerance; natural products; osthole (OST)
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Atopic diseases, including atopic dermatitis (AD), food and environmental allergies, and asthma, constitute a major public health problem worldwide. Allergic inflammation is one of the immune system’s protective responses against pathogens and endogenous noninfectious molecules. The recognition of foreign substances by immune cells leads to the synthesis of various pro-inflammatory cytokines and chemokines involved in inflammation. The release of pro-inflammatory mediators leads to further engagement of circulating immune cells at the site of infection, resulting in the synthesis of prostaglandins, reactive oxygen species (ROS) and cyclooxygenase-2 (COX -2), thereby exacerbating inflammation. According to the WHO, chronic inflammation and its associated diseases pose serious challenges to the health of the world in the near future. This realization has led to increased efforts to explore new therapeutic approaches against inflammatory diseases. Various synthetic drugs have been used to control and treat inflammatory diseases, with varying results. However, there certain health concerns can arise when these synthetic drugs are taken for a long period of time. Therefore, safe and cost-effective therapeutic alternatives need to be developed to combat this threat in a sustainable manner. Natural ingredients have been used for many millennia to treat various human ailments. Nearly 35% of the drugs and their derivatives approved by the FDA between 1981 and 2010 were derived from natural sources.

The aim of this Special Issue is to investigate the anti-inflammatory and anti-allergic potential of new natural products in alleviating symptoms of allergic diseases or combating their mechanisms of action.

Dr. Natalia Karolina Kordulewska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • anti-inflammatory
  • anti-allergic
  • natural products
  • allergic diseases
  • allergic inflammation

Published Papers

There is no accepted submissions to this special issue at this moment.
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