Special Issue "Total Parenteral Nutrition Preparations, Challenges in Formulations and Compatibility Studies"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: closed (30 October 2023) | Viewed by 463

Special Issue Editors

1. Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain
2. Pharmacy Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
3. CIBER de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid, Spain
Interests: pharmacology; stability studies; precision medicine
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Interests: parenteral nutrition; stability studies; nutrition support
1, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
2. Faculty of Health Science, Blanquerna – Universitat Ramon Llull, Barcelona, Spain
Interests: stability studies; pharmacotherapy; pharmaceutical care

Special Issue Information

Dear Colleagues,

Parenteral nutrition (PN) is a valuable clinical approach for patients at risk of malnutrition who are unable to receive nutrients through the gastrointestinal tract. PN is included in the ISMP’s list of high-alert medication. Standard procedures and a close monitoring are needed to achieve optimal patient outcomes and ensure patient safety.

As for PN preparations, their stability and sterility are still major concerns and potentially pose a high risk to patients. There is a wide range of variables that can compromise stability, considering that PN preparations are lipid emulsions that include components such as calcium or phosphate that may lead to precipitation and/or emulsion break-up. Additionally, the Y-site administration of drugs with TPN can affect the admixture’s stability, among other potential critical factors.

Further studies are needed to generate more evidence regarding the abovementioned challenges and to increase the knowledge in this area. In this Special Issue, we aim to draw together research from experts in the field that focuses on the concerns affecting PN preparations.

Dr. Pau Riera
Dr. Jan Thomas De Pourcq
Dr. Noe Garin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • parenteral nutrition
  • stability
  • sterility
  • drug–TPN compatibility
  • formulation challenges

Published Papers

There is no accepted submissions to this special issue at this moment.
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