Special Issue "Magnetic Nanoparticles (MNPs) in Biomedical Applications"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: 15 March 2024 | Viewed by 1844

Special Issue Editor

Department of Chemistry, University of KwaZulu-Natal, Private Bag X 54001, Durban 4000, South Africa
Interests: combination of photodynamic therapy and magnetic hyperthermia; iron oxide magnetic nanoparticles

Special Issue Information

Dear Colleagues,

Magnetic nanoparticles are currently reshaping medical nanotechnologies and applications. Publications on biomedical applications of magnetic nanoparticles increased by more than three orders of magnitude over the past two decades, with a corresponding increase in patents, clinical trials, clinical applications, and medical devices. Examples include magnetic resonance imaging, magnetic hyperthermia for cancer, bone, brain, liver, and pancreas therapies, targeted drug delivery, tissue engineering, biosensors, and other biomedical applications. Synthetic and characterization approaches have also increased, providing insights into an increasing range of nano-morphologies including spheres, crystals, rods, stars, flowers, wires, and sheets, and these are increasingly engineered into multi-functional nanoconjugates used in bio-environmental and stimulus-responsive drug delivery and release.

Paramagnetic and superparamagnetic metal, alloy, chalcogenide, and ferrite nanoparticles of iron, nickel, cobalt, gadolinium, and other metals are commonly used. Biocompatibility is achieved through polymeric, biomimetic membrane encapsulation, cloaking, and functionalization with target cell membrane and internal component molecules such as aptamers and folate for cancer cell targeting. These developments have led to novel innovations promising reduction of disease burden. The special issue will publish research and review articles on the foregoing and other relevant reflections, perspectives, and research investigations.

The range of articles includes disease detection and diagnosis, therapeutic applications, image-guided theragnostic, combination therapies, design and fabrication of nanoconjugates for biomedical applications, in-vitro, in-vivo, and clinical applications, and biomedical devices. Environmental applications aimed at reducing the burden of disease are considered to be an important part of biomedical disease prevention.

Prof. Dr. Sandile Phinda Songca
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • magnetic nanoparticles
  • magnetic resonance imaging
  • magnetic hyperthermia
  • cancer therapy
  • bone therapy
  • magnetically targeted drug delivery
  • magnetic hyperthermia drug release
  • antimicrobial
  • tissue engineering
  • biosensors

Published Papers (1 paper)

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12 pages, 8102 KiB  
Manipulation of New Fluorescent Magnetic Nanoparticles with an Electromagnetic Needle, Allowed Determining the Viscosity of the Cytoplasm of M-HeLa Cells
Pharmaceuticals 2023, 16(2), 200; https://doi.org/10.3390/ph16020200 - 29 Jan 2023
Viewed by 1243
Magnetic nanoparticles (MNPs) have recently begun to be actively used in biomedicine applications, for example, for targeted drug delivery, in tissue engineering, and in magnetic resonance imaging. The study of the magnetic field effect on MNPs internalized into living cells is of particular [...] Read more.
Magnetic nanoparticles (MNPs) have recently begun to be actively used in biomedicine applications, for example, for targeted drug delivery, in tissue engineering, and in magnetic resonance imaging. The study of the magnetic field effect on MNPs internalized into living cells is of particular importance since it allows a non-invasive influence on cellular activity. There is data stating the possibility to manipulate and control individual MNPs utilizing the local magnetic field gradient created by electromagnetic needles (EN). The present work aimed to demonstrate the methodological and technical approach for manipulating the local magnetic field gradient, generated by EN, novel luminescent MNPs internalized in HeLa cancer cells. The controlling of the magnetic field intensity and estimation of the attractive force of EN was demonstrated. Both designs of EN and their main characteristics are also described. Depending on the distance and applied voltage, the attractive force ENs ranged from 0.056 ± 0.002 to 37.85 ± 3.40 pN. As a practical application of the presented, the evaluation of viscous properties of the HeLa cell’s cytoplasm, based on the measurement of the movement rate of MNPs inside cells under impact of a known magnetic force, was carried out; the viscosity was 1.45 ± 0.04 Pa·s. Full article
(This article belongs to the Special Issue Magnetic Nanoparticles (MNPs) in Biomedical Applications)
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