Special Issue "Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs 2024"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: 25 March 2024 | Viewed by 43

Special Issue Editor

Departamento Ciencias Biomédicas, Facultad de Farmacia, Universidad de Alcalá, Alcalá de Henares, 28871 Madrid, Spain
Interests: drug formulation; pharmaceutical technology; formulation development and characterization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The processes of solubilization and controlled release of drugs that are not very soluble in water are of great relevance to the pre-formulation of drugs in pharmaceutical developments.

In recent years, a large number of drugs have been industrialized, but almost 70% of them have low solubility in water, which limits their dissolution rate and, consequently, their bioavailability. Undoubtedly, it is a problem with far-reaching repercussions for the pharmaceutical industry, so the discovery of new technological tools for the hydrosolubilization of drugs that do not affect their physical–chemical and therapeutic properties will constitute an extraordinary achievement.

On the other hand, from a pharmacological point of view, the search for knowledge about the interaction mechanism and the different properties of drug-controlled release systems is currently of great importance in drug formulation, especially in relation to their efficacy therapy, as well as achieving the correct amount of active ingredient, the right time and the precise place of action.

This Special Issue is dedicated to the latest advances in solubilization and controlled release processes for poorly soluble drugs. We invite authors to submit original research or review articles on these topics, including the development of novel solubilization strategies, as well as innovative alternative methods to obtain new controlled-release pharmaceutical forms, suitable for a specific patient and the pathology to be treated, without forgetting the best form of administration to obtain the optimal efficacy and safety of the drugs.

Prof. Dr. María Ángeles Peña Fernández
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • drug formulation
  • solubilization
  • controlled release systems
  • solubility
  • poor water-soluble drugs

Published Papers

This special issue is now open for submission.
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