Special Issue "Pharmacotherapy of Dyslipidemias"
Deadline for manuscript submissions: 30 November 2023 | Viewed by 2686
Interests: bioactive peptides; cardiovascular; diabetes; dyslipidemia; endothelium; hypertension; medicinal plants; natural products; pharmacology; preclinical toxicology; vasorelaxant
Special Issues, Collections and Topics in MDPI journals
Interests: arterial hypertension; diabetes; effects of physical training; general and exercise physiology; health conditions of population groups; nutrition and public health; obesity; pharmacology of natural products
Dyslipidemia is a clinical condition characterized by changes in plasma lipoprotein concentrations in relation to reference values considered as normal. The increase in the concentration of blood circulating lipids induces an inflammatory process which leads to endothelial damage and then the formation of atherosclerosis plaques, an important cardiovascular risk factor responsible for complications such as acute myocardial infarction and stroke. Most of these complications are a result of atherosclerotic plaque rupture or erosion, thrombin generation, platelet activation, and cloth formation. Many hypotheses about its pathogenesis and progression suggest the involvement of oxidative stress, considering that LDL oxidation is a fundamental factor in initiating the atherogenic process. In this sense, the presence of lipid peroxidation products can trigger oxidative changes in LDL particles. Such lesions can be prevented or reduced by the action of antioxidant phytochemicals present in fruits and vegetables, which have been shown to be a promising alternative to the adverse effects associated with the use of classic lipid-lowering drugs, such as myalgia and the elevation of hepatic transaminases induced using statins. In this sense, this Special Issue focuses on non-clinical and clinical studies which report advances in the pharmacological therapy of dyslipidemias, from classical treatments to novel promising compounds synthetically obtained or from natural sources. Both original and review articles are welcomed.
Dr. Daniel Arcanjo
Dr. Maria do Carmo de Carvalho e Martins
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- endothelial dysfunction
- fatty acids
- high-fat diet
- polyunsaturated fatty acids