Special Issue "Triazole and Derivatives in Medicinal Chemistry"
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 15 February 2024 | Viewed by 832
Special Issue Editor
Interests: organic chemistry; organic synthesis; catalysis; medicinal chemistry; pharmacy
Special Issue Information
Dear Colleagues,
The development of modern medicinal chemistry has tightened the heterocycles with biological activities. Several derivatives of heterocyclic compounds have found applications in various medical fields. Triazole, a five-member heterocycle with 3 nitrogen and 2 carbon atoms, is a significant backbone in medicinal chemistry. This backbone could be found in the structure of many commercial drugs. Since it is readily available through click chemistry to create compound collections against various diseases, it has become an emerging area of interest for medicinal chemists. As is widely known, triazole is the building block for numerous drugs with therapeutic benefits, including antimicrobial, antiviral, anticancer, anti-inflammatory, analgesic, anti-tuberculosis, and antidiabetic activities. In addition, this compound can form complexes with different compounds to form materials with catalytic and biological activities. Regarding the significance of this heterocycle, several researchers have focused on the synthesis of novel compounds based on triazoles and studying their biological activities. Although research efforts are focusing on the development of synthetic triazole analogs, there is still plenty of room for a breakthrough in drug discovery in this field. The potential therapeutic benefits of this moiety have motivated medicinal chemists to create innovative triazole derivatives.
This Special Issue of Pharmaceuticals focuses on "Triazole and Derivatives in Medicinal Chemistry” and invites both reviews and original articles regarding their findings in this field.
I look forward to receiving your contributions.
Dr. Saeed Bahadorikhalili
Guest Editor
Manuscript Submission Information
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Keywords
- triazole
- heterocycles
- medicinal chemistry
- pharmaceutical chemistry
- organic synthesis
- catalytic organic synthesis
- bioactivity
- organocatalysis