Special Issue "Novel Imidazole Derivatives in Medicinal Chemistry"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 20 February 2024 | Viewed by 152

Special Issue Editors

Dr. Dorota Olender
E-Mail Website
Guest Editor
Department of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, Poznan, Poland
Interests: organic synthesis; green chemistry; heterocycles; nitro group; antimicrobial and anticancer activity; nitroimidazoles; curcuminoids; chalcones
Department of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, Poznan, Poland
Interests: organic synthesis; heterocycles; nitro group; antimicrobial and antituberculosis activity; nitroimidazoles
Department of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, Poznan, Poland
Interests: organic medicinal chemistry; small molecules; heterocyclic compounds; isoprenoids; drug design; synthetic processes; MAOS; drug–drug conjugates; hybrid compounds as “molecular consortia”
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Special Issue Information

Dear Colleagues,

Current concepts related to searching for new bioactive products, mainly including original active substances with potential application in pharmacy and medicine, are based on compounds with a previously determined structure, well-known properties and biological activity profile. Medicinal chemistry is the discipline concerned with determining the influence of chemical structure on biological activity. The practice has developed from an empirical background, involving the organic synthesis of new compounds mainly based on the modification of their structure and the identification of their biological activity. Compounds containing the imidazole moiety exhibit a wide range of biological activities. The imidazole skeleton is present in various natural compounds, such as histidine, histamine and pilocarpine alkaloids, and synthetic bioactive compounds, including cimetidine, losartan, fungicides or herbicides. These azoles show a broad spectrum of biological activities, such as anticancer, antifungal, antiviral, antibacterial, antitubercular, antiparasitic, antihistaminic, anti-inflammatory and antineuropathic.

Considering the above, we invite researchers to publish their findings on the synthesis and biological applications of imidazole derivatives, while highlighting the importance of using these molecules as a basis for developing new drugs.

This Special Issue aims to summarize the state of the art and the latest findings published in the imidazole field, as well as elucidate the future directions of these compounds in medicinal chemistry.

Dr. Dorota Olender
Dr. Justyna Żwawiak
Prof. Dr. Lucjusz Zaprutko
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • imidazole
  • nitroimidazole derivatives
  • biological activities
  • synthesis
  • heterocyclic drug discovery

Published Papers

This special issue is now open for submission.
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