Special Issue "Application of Membrane Transporters in Drug Development"
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 432
Special Issue Editors
Interests: drug transporter; pharmaceutical excipients; drug delivery; formulation development; pharmacological barriers
Interests: controlled and sustained drug release; oral drug delivery systems; biopharmaceutics; pharmacokinetics; drug transporters
Special Issue Information
Dear Colleagues,
More than 400 membrane transporters in two major superfamilies—ATP-binding cassette (ABC) and solute carrier (SLC)—have been discovered in the human genome and are widely expressed throughout the body. Numerous studies have demonstrated that these transporters play key roles in the absorption, distribution, metabolism and excretion (ADME) properties of drug substances, altering their therapeutic and adverse effects. Additionally, drug–drug interactions (DDIs) are observed due to their transporter-related features, triggering follow-up clinical studies. Thus, a comprehensive understanding of the interactions between transporters and drugs can lead to breakthroughs in the discovery and development of new molecules.
This Special Issue attempts to highlight the latest advances in the application of transporter information in drug discovery and development. We are pleased to invite you to contribute your original research or review articles on the following areas: mechanisms on the variability of transporters caused by genetic, epigenetic and other factors, innovative methods for studying and predicting drug–transporter interactions and the design of transporter-mediated drugs.
Dr. Mai Yang
Prof. Dr. Zheng Cai
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- membrane transporters
- ABC
- SLC
- transporter-mediated drug
- drug–drug interaction
- drug development
- pharmacological barriers
