Special Issue "Herbal Medicine for the Treatment of Fatty Liver Disease"
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 250
Special Issue Editors
Interests: epidemiology; network pharmacology; obesity; cancer; kidney disease
Interests: hepatocellular carcinoma; surgical oncology; minimal invasive surgery
Special Issue Information
Dear Colleagues,
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder that has gradually become one of the most common non-communicable diseases in recent decades. On the other hand, as a chronic disease with heterogenous etiologies, complicated pathogenesis, and multiple co-morbidities, NAFLD may progress to non-alcoholic steatohepatitis (NASH) and even cirrhosis if it cannot be managed appropriately. However, despite the impact on the healthcare system, the medical therapies for NAFLD are still limited, for example, GLP-1 and PPARγ mimetics. Therefore, new agents with or without non-pharmacological treatments (exercise, lifestyle or diet modification, etc.) are still needed.
Herbal medicine (HM) has been used in many countries for thousands of years. It is reported that several HMs have anti-NAFLD effects through modulating lipid metabolisms, oxidative stress, autophagy, and other mechanisms. For instance, Torenia concolor Lindley var. formosana Yamazaki has been found to be beneficial to alleviate inflammation effects from lipid accumulation in fat-cell models. Resveratrol has been reported to have the ability to enhance autophagy and reduce oxidative stress and fibrosis. On the other hand, management of the NAFLD-related co-morbidities, such as obesity, metabolic syndrome, hyperlipidemia, and polycystic ovarian syndrome, is also essential to deal with NAFLD since there are complex interactions between NAFLD and its co-morbidities.
The purpose of this Special Issue is to investigate the feasibility of HM in managing NAFLD. Clinical, in vitro, or in vivo studies are all welcome for submission to this Special Issue.
Dr. Hsing-Yu Chen
Dr. Chao-Wei Lee
Guest Editors
Manuscript Submission Information
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Keywords
- non-alcoholic fatty liver disease
- herbal medicine
- clinical trial
- cohort
- case–control
- in vivo
- in vitro
