Special Issue "Pathogen Legionella pneumophila"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (30 September 2016) | Viewed by 23035
Interests: drug design; metalloenzymes; carbonic anhydrases; anticancer agents; antiinfectives; sulfonamides; coumarins
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Legionella pneumophila is a Gram-negative environmental bacterium that normally infects amoebae. It was discovered in 1976 when it provoked a life-threatening pneumonia-like disease in many participants at the 58th Annual Convention of the American Legion in Philadelphia. This condition was subsequently dubbed Legionnaires’ disease, or legionellosis. When the bacterial pathogen was characterized in detail, it was shown that a large number of its subspecies and serovars are widespread in nature. It is now known that L. pneumophila and the related species L. longbeachae are responsible for legionellosis in humans. These pathogens are increasingly spread all over the world through the development of artificial water systems for air conditioning, cooling towers, and aerosolizing devices, among other applications, and they have started to show resistance to the clinically used antibiotics. This issue of the Pathogens will bring together papers in all fields, starting with molecular biology and ending with novel antibiotic development related to L. pneumophila.
Professor Claudiu T. Supuran
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- Legionella pneumophila
- drug resistance
- bacterial evolution
- pathogen survival
- drug development