Special Issue "Host-Pathogen Interaction in Respiratory Infections of the Neonate"

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 138

Special Issue Editors

Department of Microbiology and Immunology, Pennsylvania State University College of Medicne, Hershey, PA, USA
Interests: perinatal and post-natal host defense functions of pulmonary surfacatnt; respiratory virus pathogenesis; bronchopulmonary dysplasia; pulmonary hypertension
Dr. Alison J. Carey
E-Mail Website
Co-Guest Editor
Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA
Interests: Staphylococcus aureus; Staphylococcal infections; immunology; neonatal intensive care; infection control; influenza; respiratory viral infections; flow cytometry; neonatal sepsis

Special Issue Information

Dear Colleagues,

The respiratory tract consists of specialized microbial ecosystems that are seeded during and immediately after birth. Disrupted development of the respiratory microbiome early in life is associated with increased susceptibility to respiratory infections later in life. Viral infections early in life may increase the risk of respiratory infections in the first year of life. Lung infection remains the leading cause of infant and child death worldwide and is responsible for a significant morbidity burden. The exact mechanisms of children developing recurrent or severe respiratory tract infections while others remain healthy are still unclear. Therefore, research on this aspect is of great significance for protecting the respiratory health of newborns.

In this Special Issue, we aim to bring together researchers from across the field of pediatric medicine to submit studies that address unique aspects of host–virus interactions at the maternal–fetal interface.

This Special Issue includes but is not limited to the following topics:

  1. Placental factors in host–virus immunity;
  2. Neonatal and infant vaccination strategies;
  3. Developmental changes during early childhood in viral immunity;
  4. Effects of the microbiome on immunity in health and viral disease;
  5. Critical periods in early life for laying the foundations for future response to viral infections;
  6. Trained immunity.

Dr. Zissis C. Chroneos
Dr. Alison J. Carey
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • maternal–fetal immune interaction
  • neonate
  • respiratory infection
  • host-pathogen interaction
  • immunology

Published Papers

This special issue is now open for submission.
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