Bacterial Biofilm, Genomics and Virulence

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 955

Special Issue Editors

Department of Food Science and Technology, Chung-Ang University, Anseong 456-756, Gyunggido, Republic of Korea
Interests: food safety; biofilm; virulence; quorum sensing; food processing
Institute of Food Science and Technology, Pukyong National University, Busan, Republic of Korea
Interests: food science; biofilm; food packaging

Special Issue Information

Dear Colleagues,

The formation of biofilm is a survival strategy for bacteria and fungi to adapt to their living environment, especially in a hostile environment. Under the protection of biofilm, microbial cells in biofilm become tolerant and resistant to antibiotics and immune responses, which increases difficulties for the clinical treatment of biofilm infections. Despite the enormous efforts of academic researchers, clinicians, and industry in recent years, many biofilm pathogenesis mechanisms remain unanswered. Hence, it is imperative to develop new strategies to control biofilm infections. 

This Special Issue will summarize the latest progress in the treatment of biofilm infections and scientific investigations, discuss the diagnosis and treatment of different biofilm infections, and introduce promising laboratory progress, which may contribute to the prevention or cure of biofilm infections. 

Potential topics include but are not limited to:

  • Bacterial biofilm formation and biofilm pathogenesis;
  • Biofilm tolerance to antimicrobials;
  • The detection of biofilm infections;
  • Host–biofilm interactions; 
  • The role of biofilms in clinical infection;
  • The discovery and evaluation of antibiofilm agents.

Dr. Md. Furkanur Rahaman Mizan
Dr. Vikash Chandra Roy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biofilm
  • virulence
  • antibiofilm agents
  • antimicrobials
  • host–biofilm interactions

Published Papers (1 paper)

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Research

24 pages, 15946 KiB  
Article
Characterization of a Novel Species of Legionella Isolated from a Healthcare Facility: Legionella resiliens sp. nov
by Sandra Cristino, Maria Rosaria Pascale, Federica Marino, Carlo Derelitto, Silvano Salaris, Massimiliano Orsini, Stefano Squarzoni, Antonella Grottola and Luna Girolamini
Pathogens 2024, 13(3), 250; https://doi.org/10.3390/pathogens13030250 - 14 Mar 2024
Viewed by 560
Abstract
Two Legionella-like isolates, 8cVS16T and 9fVS26, were isolated from a water distribution system (WDS) in a healthcare facility. Cells were Gram- and Ziehl Neelsen-stain-negative, rod-shaped, motile, and exhibited a blue-white fluorescence under Wood’s lamp at 365 nm. The strains grew in [...] Read more.
Two Legionella-like isolates, 8cVS16T and 9fVS26, were isolated from a water distribution system (WDS) in a healthcare facility. Cells were Gram- and Ziehl Neelsen-stain-negative, rod-shaped, motile, and exhibited a blue-white fluorescence under Wood’s lamp at 365 nm. The strains grew in a range of 32–37 °C on BCYE with L-cysteine (Cys+), GVPC, and MWY agar medium, with a positive reaction for oxidase, catalase, and gelatinase. The dominant fatty acids were summed features 3 (C16:1ω7c/C16:1ω6c) (27.7%), C16:0 iso (17.5%), and C16:0 (16.3%), and Q13 as the major ubiquinone. The mip and rpoB gene sequences showed a similarity of 96.7% and 92.4%, with L. anisa (ATCC 35292T). The whole genomes sequencing (WGS) performed displayed a GC content of 38.21 mol% for both. The digital DNA-DNA hybridization (dDDH) analysis demonstrated the separation of the two strains from the phylogenetically most related L. anisa (ATCC 35292T), with ≤43% DNA-DNA relatedness. The Average Nucleotide Identity (ANI) between the two strains and L. anisa (ATCC 35292T) was 90.74%, confirming that the two isolates represent a novel species of the genus Legionella. The name proposed for this species is Legionella resiliens sp. nov., with 8cVS16T (=DSM 114356T = CCUG 76627T) as the type strain. Full article
(This article belongs to the Special Issue Bacterial Biofilm, Genomics and Virulence)
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