Special Issue "Antibody-Based Assay for Infectious Related Diseases"
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".
Deadline for manuscript submissions: 29 February 2024 | Viewed by 173
Interests: Epstein-Barr Virus; immune response to virus related malignancies; immune response to SARS-CoV-2; immunological-based biomarkers
Interests: Epstein-Barr virus and other viruses; infection-related cancer; immune aspect of pathogen infections and diseases; molecular mechanism of host-pathogen interaction
The affordability and ease of deployment of genomic detection technology have enabled genomic-based testing to be available in regions of the world, particularly in the wake of the COVID-19 pandemic. Pathogen genomics-based tests aim to check infection status but have quite a narrow window period of use. Despite the widespread use of PCR-based tests in the pandemic response, antibody-based tests remain an important tool for infectious-related disease diagnosis. Antibody-based tests can be used for more diverse objectives. They reflect not only an active infection (primary infection) but also determine past infection, re-infection, reactivation upon latent state, etc. Furthermore, antibody-based tests can also confirm the need for vaccination or whether an immune response has developed against vaccination.
Nevertheless, antibody-based tests have several pitfalls, including the diversity of methods used (e.g., ELISA vs ECLIA vs Western blot detection, quantitative vs quantitative), variety of antigens used to determine infection status for the same pathogen, the determination of target population, and internal or external host factors that may inflate/deflate the results of antibody-based tests.
We invite researchers interested in discussing the development and use of antibody-based tests for the diagnosis of infectious diseases and infectious-related diseases to share their findings and opinions in this Special Issue.
The following topics are of major interest but are not limited to:
- Development of new antibody-based tests;
- Application of antibody-based tests in different infection stages;
- Antibody-based tests for detection of certain infectious diseases or infectious-related diseases;
- Antibodies as a risk factor for certain chronic diseases;
- Antibodies as prognostic factors for certain chronic diseases.
Original articles and reviews are welcome.
Dr. Jajah Fachiroh
Dr. Dewi Kartikawati Paramita
Dr. Ines Atmosukarto
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