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Bioactive Compounds in Potential Disease Treatment

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: closed (25 April 2024) | Viewed by 860

Special Issue Editor

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Guest Editor
Department of Medical Chemistry, Medical University of Gdansk, 80-210 Gdansk, Poland
Interests: bioactive compounds; protein tyrosine phosphatases; PTP YopH virulence factor

Special Issue Information

Dear Colleagues,

To comprehend how bioactive compounds affect people’s health, research is being conducted. Many different natural dietary products, including fruits (citric acid), coffee (caffeic acid), spices (cinnamic acid, etc.) include these substances. Some of these substances have already demonstrated various possible positive effects on humans’ health and illness prevention in in vitro or in vivo investigations. Due to the wide range of component types and activities, including inflammation, metabolism, and antimicrobial aspects, plant bioactive compounds are of tremendous interest. 

In light of this, we encourage you to contribute a study or professional expertise to this Special Issue "Bioactive Compounds in Potential Disease Treatment." Reviews on the impact of bioactive chemicals in potential treatments and their comorbidities, as well as clinical, experimental, and in vitro investigations, are all appreciated.

Dr. Alicja Kuban-Jankowska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • bioactive compounds
  • natural compounds
  • active compounds from plants
  • supplementary treatment

Published Papers (1 paper)

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19 pages, 976 KiB  
Usefulness of Opuntia spp. on the Management of Obesity and Its Metabolic Co-Morbidities
by Iker Gómez-García, Alfredo Fernández-Quintela, Marcela González, Saioa Gómez-Zorita, Begoña Muguerza, Jenifer Trepiana and María P. Portillo
Nutrients 2024, 16(9), 1282; - 25 Apr 2024
Viewed by 535
The plants of the Opuntia genus mainly grow in arid and semi-arid climates. Although the highest variety of wild species is found in Mexico, Opuntia spp. is widely distributed throughout the world. Extracts of these cacti have been described as important sources of [...] Read more.
The plants of the Opuntia genus mainly grow in arid and semi-arid climates. Although the highest variety of wild species is found in Mexico, Opuntia spp. is widely distributed throughout the world. Extracts of these cacti have been described as important sources of bioactive substances that can have beneficial properties for the prevention and treatment of certain metabolic disorders. The objective of this review is to summarise the presently available knowledge regarding Opuntia ficus-indica (nopal or prickly pear), and some other species (O. streptacantha and O. robusta) on obesity and several metabolic complications. Current data show that Opuntia ficus-indica products used in preclinical studies have a significant capacity to prevent, at least partially, obesity and certain derived co-morbidities. On this subject, the potential beneficial effects of Opuntia are related to a reduction in oxidative stress and inflammation markers. Nevertheless, clinical studies have evidenced that the effects are highly contingent upon the experimental design. Moreover, the bioactive compound composition of nopal extracts has not been reported. As a result, there is a lack of information to elucidate the mechanisms of action responsible for the observed effects. Accordingly, further studies are needed to demonstrate whether Opuntia products can represent an effective tool to prevent and/or manage body weight and some metabolic disorders. Full article
(This article belongs to the Special Issue Bioactive Compounds in Potential Disease Treatment)
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