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Nutrition and Lifestyle as Preventive and Therapeutic Targets for Obesity and Inflammation

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Obesity".

Deadline for manuscript submissions: closed (10 January 2023) | Viewed by 7093

Special Issue Editors

Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, 90133 Palermo, Italy
Interests: human nutrition; micronutrients; biofortified food; physical activity; gut peptides; bone remodeling and metabolism; glucose homeostasis; lipid homeostasis; systemic homeostasis; human physiology
Special Issues, Collections and Topics in MDPI journals
Department of Biology, College of Science and Health, University of Wisconsin-La Crosse, La Crosse, WI 54601, USA
Interests: gut; inflammatory bowel disease; irritable bowel syndrome; nutrition; metabolic disordres

Special Issue Information

Dear Colleagues,

Nutrition and lifestyle are key to preventing weight gain and reducing susceptibility to infections such as COVID-19. This Special Issue will accept submissions of both original research manuscripts and review articles focusing on how nutrition alone or together with lifestyle is able to prevent obesity and systemic/local inflammation. Articles exploring inflammatory bowel disease, irritable bowel syndrome and metabolic disorders will be considered for publication in this Special Issue. Articles focusing on the interactions between systemic inflammation and local inflammation (gastrointestinal tract, brain, liver, adipose tissue, bone, etc.) that provide new insights into preventive and therapeutic targets for obesity are also very welcome.

Dr. Sara Baldassano
Prof. Dr. Sumei Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • physical activity
  • exercise
  • diet
  • metabolic diseases
  • diabetes
  • inflammation
  • inflammatory bowel disease
  • irritable bowel syndrome

Published Papers (2 papers)

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Review

18 pages, 2166 KiB  
Review
Exploring the Effects of Energy Constraints on Performance, Body Composition, Endocrinological/Hematological Biomarkers, and Immune System among Athletes: An Overview of the Fasting State
Nutrients 2022, 14(15), 3197; https://doi.org/10.3390/nu14153197 - 04 Aug 2022
Cited by 2 | Viewed by 3213
Abstract
The Ramadan fasting period (RFP) means abstaining from consuming food and/or beverages during certain hours of the day—from sunrise to sunset. Engaging in exercise and sports during the RFP leads to the lipolysis of adipose tissue and an increase in the breakdown of [...] Read more.
The Ramadan fasting period (RFP) means abstaining from consuming food and/or beverages during certain hours of the day—from sunrise to sunset. Engaging in exercise and sports during the RFP leads to the lipolysis of adipose tissue and an increase in the breakdown of peripheral fat, leading to an increase in fat consumption. The effects of the RFP on functional, hematological, and metabolic parameters needs further study as existing studies have reported contradictory results. The differences in the results of various studies are due to the geographical characteristics of Muslim athletes, their specific diets, and their genetics, which explain these variations. In recent years, the attention of medical and sports researchers on the effects of the RFP and energy restrictions on bodily functions and athletic performance has increased significantly. Therefore, this brief article examines the effects of the RFP on the immune system, body composition, hematology, and the functionality of athletes during and after the RFP. We found that most sporting activities were performed during any time of the day without being affected by Ramadan fasting. Athletes were able to participate in their physical activities during fasting periods and saw few effects on their performance. Sleep and nutritional factors should be adjusted so that athletic performance is not impaired. Full article
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14 pages, 1015 KiB  
Review
Hydrolyzed Proteins and Vegetable Peptides: Anti-Inflammatory Mechanisms in Obesity and Potential Therapeutic Targets
Nutrients 2022, 14(3), 690; https://doi.org/10.3390/nu14030690 - 06 Feb 2022
Cited by 8 | Viewed by 3041
Abstract
Chronic low-grade inflammation is present in overweight and obesity, causing changes in several metabolic pathways. It impairs systemic functioning and positively feeds back the accumulation of more adipose tissue. Studies with hydrolyzed proteins and plant peptides have demonstrated a potential anti-inflammatory and immunomodulatory [...] Read more.
Chronic low-grade inflammation is present in overweight and obesity, causing changes in several metabolic pathways. It impairs systemic functioning and positively feeds back the accumulation of more adipose tissue. Studies with hydrolyzed proteins and plant peptides have demonstrated a potential anti-inflammatory and immunomodulatory effect of these peptides. However, it is challenging and necessary to explore the mechanism of action of such molecules because understanding their effects depends on their structural characterizations. Furthermore, the structure might also give insights into safety, efficacy and efficiency, with a view of a possible health application. Thus, the present narrative review aimed to discuss the mechanisms of action of hydrolyzed proteins and plant peptides as anti-inflammatory agents in obesity. Keywords and related terms were inserted into databases for the search. Based on the studies evaluated, these biomolecules act by different pathways, favoring the reduction of inflammatory cytokines and adipokines and the polarization of macrophages to the M2 phenotype. Finally, as a future perspective, bioinformatics is suggested as a tool to help understand and better use these molecules considering their applicability in pre-clinical and clinical studies. Full article
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