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Microbiome Modulation for Human Health (Closed)

A topical collection in Nutrients (ISSN 2072-6643). This collection belongs to the section "Prebiotics and Probiotics".

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Editor


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Collection Editor
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
Interests: cirrhosis; microbiome; probiotic; prebiotic; sarcopenia
Special Issues, Collections and Topics in MDPI journals

Topical Collection Information

Dear Colleagues,

The term "probiotic" was coined by the Nobel prize winner Ilia Metchnikoff more than 100 years ago, who hypothesized that health could be enhanced and senility delayed by manipulating the intestinal microbiome with bacteria found in yogurt. The development of modern, culture-independent ways to study the microbiome composition at various sites within and outside the human body has greatly enlarged our knowledge on the role of the microbiome in health and disease. However, many of these studies are descriptive and report associations rather than causality. Furthermore, there is a high demand for therapeutic strategies that utilize or target the human microbiome to prevent or treat diseases and to understand the interaction of drugs with the human gut microbiome. With this Collection of the journal Nutrients, this knowledge gap should be filled by high-quality data on the effect of "Microbiome Modulation for Human Health".

Dr. Vanessa Stadlbauer-Köllner
Collection Editor

Manuscript Submission Information

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Published Papers (1 paper)

2022

21 pages, 1092 KiB  
Review
Gut Microbiota in Psoriasis
by Mihaela Cristina Buhaș, Laura Ioana Gavrilaș, Rareș Candrea, Adrian Cătinean, Andrei Mocan, Doina Miere and Alexandru Tătaru
Nutrients 2022, 14(14), 2970; https://doi.org/10.3390/nu14142970 - 20 Jul 2022
Cited by 29 | Viewed by 7201
Abstract
Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth and defective differentiation. The link between the gut microbiota and immune system regulation opened a novel angle to understand the [...] Read more.
Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth and defective differentiation. The link between the gut microbiota and immune system regulation opened a novel angle to understand the pathogenesis of many chronic multifactorial diseases, including psoriasis. Current evidence suggests that modulation of the gut microbiota, both through dietary approaches and through supplementation with probiotics and prebiotics, could represent a novel therapeutic approach. The present work aims to highlight the latest scientific evidence regarding the microbiome alterations of psoriatic patients, as well as state of the art insights in terms of microbiome-targeted therapies as promising preventive and therapeutic tools for psoriasis. Full article
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