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Influence of Diet on Age-Related Disease: From Physiopathology to Pathogenesis

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: closed (5 February 2024) | Viewed by 2387

Special Issue Editor

1. Department of Internal Medicine, Hospital Clinic, Institut d’Investigació Biomèdica August Pi i Sunyer (IDIBAPS), University of Barcelona, Villarroel, 170, 08036 Barcelona, Spain
2. Centro de Investigación Biomédica en Red de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain
Interests: clinical nutrition; control and prevention; supplementation; chronic disease; dietary patterns; ultra-processed food consumption patterns; balanced diet; cardiometabolic risk; immune system; gut-associated microbiome
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Special Issue Information

Dear Colleagues,

The most accepted definition of sarcopenic obesity is a combination of obesity and sarcopenia, which is found mainly but not exclusively in older people (>60 years) and is associated with increased likelihood of adverse outcomes. Sarcopenic obesity is characterized by high fat mass, low muscle mass, and low muscle strength, as well as low physical functionality. Subjects with this pathology manifest comorbidities such as type 2 diabetes mellitus (T2DM), dyslipidaemia, hypertension, non-alcoholic fatty liver diseases (NAFLD), and cardiovascular disease (CVD). These obesity-related comorbidities can be accompanied by symptoms related to sarcopenia such as weakness, fatigue, higher risk of fractures, frailty, higher risk of hospitalization, worse quality of life, and higher risk of early mortality.

Therefore, sarcopenic obesity causes an increase in healthcare costs and has a negative effect on quality of life, particularly in those in the older population with a more sedentary lifestyle, more limited exercise and unhealthy dietary patterns, and other harmful habits such as smoking and excessive alcohol intake.

This special issue will highlight emerging research on the pathogenesis of sarcopenic obesity and its management and prevention and focus on dietary intake, physical activity, and exercise. We are seeking different types of manuscripts related to sarcopenic obesity, epidemiological studies, long-term clinical trials, as well as narrative and systematic reviews and meta-analyses.

Dr. Rosa Casas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • visceral fat
  • body composition
  • disability
  • muscle strength
  • obesity
  • older people
  • sarcopenia
  • physical activity
  • inflammation
  • nutrition

Published Papers (1 paper)

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Research

10 pages, 479 KiB  
Article
Association between the Intake of Different Protein Sources and Obesity Coexisting with Low Handgrip Strength in Persons near Retirement Age
by Doris Eglseer, Mariella Traxler and Silvia Bauer
Nutrients 2022, 14(21), 4684; https://doi.org/10.3390/nu14214684 - 05 Nov 2022
Cited by 3 | Viewed by 1740
Abstract
Nutrition is important for preventing and treating sarcopenic obesity/SO, proteins play a fundamental role. This study aimed at (1) identifying the association between different protein sources, other factors, and obesity coexisting with low handgrip strength and (2) evaluating differences in protein intake between [...] Read more.
Nutrition is important for preventing and treating sarcopenic obesity/SO, proteins play a fundamental role. This study aimed at (1) identifying the association between different protein sources, other factors, and obesity coexisting with low handgrip strength and (2) evaluating differences in protein intake between persons with coexistence of obesity with low handgrip strength, obesity alone, low handgrip strength alone and persons neither obese nor having low handgrip strength. This study is a secondary data analysis of SHARE-data among 5362 persons near retirement age. We used descriptive statistics, statistical tests and univariate and multiple logistic regression analyses. Prevalence of obesity coexisting with low handgrip strength was 4.8%. Participants with low handgrip strength had the significantly lowest intake of all protein groups, followed by participants with obesity and low handgrip strength (p < 0.001). Daily intake of meat/fish (0.56, CI 0.40–0.79), age (1.07, CI 1.03–1.11), two or more chronic diseases (2.22, CI 1.69–2.93), one or more limitations concerning instrumental activities of daily living (2.23, CI 1.60–3.11), and moderate activity more than once a week (0.44, CI 0.33–0.57) were significantly related factors regarding obesity coexisting with low handgrip strength. Findings suggest that a daily intake of meat/fish is associated with lower odds of suffering from obesity with low handgrip strength in retirement-aged persons. Further studies are needed for specific recommendations regarding different protein sources for obese persons with low muscle mass and/or strength. Full article
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