Plant-Based Foods and Their Bioactive Components: Effects on Cardiometabolic Disorders and Related Molecular Mechanisms

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 25 October 2024 | Viewed by 98

Special Issue Editors

Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science Technology and Research (A*STAR), 30 Medical Drive, Singapore 117609, Singapore
Interests: phytochemicals; probiotics; prebiotics; gut microbiota; nutrition; functional food
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Research Center for Plants and Human Health, Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, National Agricultural Science and Technology Center, Chengdu 610213, China
Interests: food authentication; polyphenol; MS-based metabolomics; functional food; chemometrics
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Guest Editor
College of Food Science, Southwest University, Chongqing, China
Interests: nutritional and functional effect of tea and natural products; development of tea products (preliminary processing, deep processing); evaluation of tea flavor quality characteristics

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Guest Editor
Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Province Engineering Technology Research Center of Coarse Cereal Industrialization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China
Interests: dietary fiber; structural characterization; chemical modification; quality evaluation; metabolic disorders; gut microbiota
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Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong 999077, China
Interests: polyphenol; phytochemical; functional gut bacteria; probiotics; phytochemical–gut microbiota interaction; metabolic disease; mass spectrometry-based metabolomics
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Special Issue Information

Dear Colleagues, 

Cardiometabolic disorders, such as metabolic syndrome, cardiovascular diseases, diabetes, obesity, non-alcoholic fatty liver disease, and certain types of cancers, are a significant global health concern, which require multi-faceted management approaches, such as individual lifestyle and dietary changes as well as innovative prevention and treatment strategies.

Plant-based foods, such as fruit, vegetables, whole grains, legumes, nuts, spices, wine, and certain functional plants, contain numerous bioactive components such as phytochemicals (e.g., polyphenols), vitamins, polysaccharides, dietary fibers, and bioactive peptides, which have been demonstrated to exhibit versatile bioactivities such as antioxidant, anti-inflammatory, hypotensive, hypoglycemic, hypolipidemic, anti-obesity, anti-diabetic, and anti-cancer properties. It is essential to prompt research on the potential roles of plant-based foods and their bioactive components in the prevention and treatment of cardiometabolic disorders.

The molecular mechanisms underlying the effects of plant-based foods and their bioactive components on cardiometabolic disorders are complex and multifaceted, involving metabolic pathway modulation, gene expression regulation, oxidative stress and inflammation inhibition, insulin sensitivity improvement, and gut microbiota modulation, among others.

This Special Issue welcomes authors to submit original research articles or reviews addressing the health impacts of plant-based foods and their bioactive components on cardiometabolic disorders. Potential topics include, but are not limited to, the following:

  • Antioxidant and anti-inflammatory properties of plant-based foods and their bioactive components;
  • Effects and underlying mechanisms of plant-based food bioactive components on glucose metabolism, lipid metabolism, insulin sensitivity, and cancer cells;
  • Health impacts of plant-based foods and their bioactive components on body weight regulation and obesity management;
  • Synergistic effects of plant-based foods in the management of cardiometabolic disorders;
  • The interaction of plant-based foods or their bioactive components with the gut microbiome and related health impacts on cardiometabolic disorders;
  • Clinical trials evaluating the cardiometabolic benefits of plant-based foods or their bioactive components.

Dr. Ren-You Gan
Dr. Hongyan Liu
Prof. Dr. Liang Zeng
Prof. Dr. Dingtao Wu
Dr. Danyue Zhao
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • fruit and vegetables
  • grains and legumes
  • dietary bioactive compounds
  • phytochemicals
  • flavonoids
  • polysaccharides
  • cardiometabolic disorders
  • cancer
  • gut microbiome

Published Papers

This special issue is now open for submission.
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