Special Issue "Nutrition and Exercise Interventions on Skeletal Muscle Physiology, Injury and Recovery: From Mechanisms to Therapy"
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Sports Nutrition".
Deadline for manuscript submissions: 15 September 2023 | Viewed by 9693
Special Issue Editors
Interests: skeletal muscle physiology; physical exercise; muscle metabolism; inflammation; insulin sensitivity; obesity and diabetes
Interests: ultrasound therapy; muscle disuse; fish oil supplementation; protein metabolism; muscle atrophy; muscle recovery
Interests: nutritional interventions; muscle physiology; muscle damage; inflammation; physical exercise; muscle recovery
Special Issue Information
Dear Colleagues,
The present Special Issue aims to join efforts towards the comprehension of the effects of nutrition and physical exercise on skeletal muscle physiology, injury, and recovery, using different experimental models (cells, animals, and humans) in both healthy and pathological conditions. Of particular interest, studies addressing cellular and molecular mechanisms involved in these processes, including energy metabolism, inflammatory pathways, oxidative stress regulation, mitochondrial function alteration, and gene expression control are welcome. We also welcome papers targeting the identification of cellular and molecular targets of nutritional interventions and physical exercise for the treatment and/or prevention of skeletal muscle injury and recovery.
Prof. Dr. Sandro Massao Hirabara
Prof. Dr. Gabriel Nasri Marzuca Nassr
Prof. Dr. Maria Fernanda Cury Boaventura
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- physical exercise
- nutritional intervention
- inflammation
- oxidative stress
- metabolism
- molecular targets
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Effectiveness of Whey Protein Supplementation During Resistance Exercise Training on Skeletal Muscle Mass and Strength in Older People with sarcopenia: A systematic review and meta-analysis
Authors: Iván Cuyul-Vásquez; José Pezo-Navarrete; Cristina Vargas-Arriagada; Cynthia Ortega-Díaz; Walter Sepúlveda Loyola; Sandro Massao Hirabara; Gabriel Nasri Marzuca-Nassr
Affiliation: Universidad de La Frontera, Faculty of Medicine, Department of Rehabilitation Sciences, Temuco, 4811230, Chile.
Abstract: Objective: To determine the effectiveness of whey protein supplementation during resistance exercise training (RET) versus RET with or without placebo on skeletal muscle mass and strength, and physical performance in older people with sarcopenia.
Methods: Electronic searches in the PubMed, Embase, Scopus, Web of Science, LILACS, SPORTdiscus, Epistemonikos, and CINAHL databases were performed until January 20, 2023. Randomized clinical trials conducted in sarcopenic adults from 60 years or older, were included. The studies had to compare the effectiveness of the addition of supplements based on concentrated, isolated, or hydrolyzed whey protein (WP) during RET and compare it with RET with or without placebo on skeletal muscle mass and strength changes. The study selection process, data extraction, and risk of bias assessment were carried out by two independent reviewers.
Results: Seven randomized clinical trials (591 participants) were included and five of them provided data for quantitative synthesis. The overall pooled standardized mean difference (SMD) estimate did not show statistically significant differences between RET plus WP versus RET with or without placebo for skeletal muscle mass, according to appendicular muscle index (SMD = 0.25; 95% CI, -0.01 to 0.50; P = 0.06; I2 = 41.86%, P = 0.142) and appendicular skeletal muscle mass (MD = 0.96 Kg; 95% CI, -0.61 to 2.54; P = 0.23; I2 = 61.19%, P = 0.076). The overall pooled SMD estimate showed statistically significant differences in favor of the RET plus WP group for handgrip strength (SMD = 0.64; 95% CI, 0.16 to 1.11; P = 0.008; I2 = 81.85%, P < 0.001). The narrative synthesis revealed discordance between the results of the studies on physical performance.
Conclusions: The WP supplementation during RET is effective in increasing handgrip strength in people with sarcopenia compared to RET with or without placebo. However, no differences were found for skeletal muscle mass. The evidence quality was very low according to the GRADE approach. Further research is needed in this research field.
PROSPERO register number: CRD42023391714.
