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Enhancement of Muscle Mass and Function by Nutritional Supplementation in the Older Population

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: closed (15 August 2023) | Viewed by 2906

Special Issue Editor


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Guest Editor
Department of Integrative Health Science, Stetson University, DeLand, FL, USA
Interests: sarcopenia; protein supplementation; protein synthesis; aging; frailty

Special Issue Information

Dear Colleague,

This special nutrition issue, titled "Enhancement of muscle mass and function by nutritional supplementation in the older population" welcomes submissions reporting original research or reviewing the scientific literature.

The loss of muscle mass and function associated with aging is a continuing concern, and factors contributing to its development have been identified. These factors include lost alpha motor neurons, increased pro-inflammatory cytokines, decreased physical activity, and decreased androgen and estrogen levels. Moreover, insufficient food intake may also be a major factor. Therefore, nutritional interventions may play an important role in the improvement of muscle mass and performance in older adults. We would like to summarize and review the effects of nutritional intervention and types of nutritional supplements on muscle mass and function, as well as metabolism, in older adults.

Dr. Matthew Schrager
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sarcopenia
  • protein supplementation
  • protein synthesis
  • aging
  • frailty

Published Papers (1 paper)

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Research

25 pages, 556 KiB  
Article
A Randomized, Double-Blind, Controlled Trial Assessing If Medium-Chain Triglycerides in Combination with Moderate-Intensity Exercise Increase Muscle Strength in Healthy Middle-Aged and Older Adults
by Keiichi Kojima, Haruna Ishikawa, Shinji Watanabe, Naohisa Nosaka and Tatsushi Mutoh
Nutrients 2023, 15(14), 3275; https://doi.org/10.3390/nu15143275 - 24 Jul 2023
Cited by 4 | Viewed by 2571
Abstract
An adequate nutritional intake is recommended for the prevention of physical frailty and sarcopenia. In particular, medium-chain fatty acids (MCFAs) are reportedly important for muscle strength in nursing home residents. However, the effects of MCFAs on healthy adults at risk for frailty remain [...] Read more.
An adequate nutritional intake is recommended for the prevention of physical frailty and sarcopenia. In particular, medium-chain fatty acids (MCFAs) are reportedly important for muscle strength in nursing home residents. However, the effects of MCFAs on healthy adults at risk for frailty remain unknown. Hence, a randomized, placebo-controlled study was conducted to investigate the effects of 12 weeks of medium-chain triglycerides (MCTs) intake and walking on muscle mass and function in healthy, sedentary, middle-aged and older adults with a low body mass index. Three MCT intake groups with different amounts of octanoic and decanoic acid intake were compared with a control group. After 12 weeks, knee extension strength increased in all groups, with the increases in all MCT intake groups being significantly higher than those in the control group (p < 0.05). Grip strength significantly increased from baseline in the MCT 6 g/day intake group (p < 0.05). The combination of aerobic exercise and MCT intake may be effective in preventing decline in muscle strength and promoting increase in muscle strength as they can improve muscle energy production, thereby contributing to the maintenance of good health for middle-aged and older adults at high risk for frailty and sarcopenia. Full article
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