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Dietary Supplements in Obesity and Weight Loss Treatments

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Obesity".

Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 1561

Special Issue Editor


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Guest Editor
1. Food & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain
2. Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, University of Valencia-Health Research Institute La Fe, 46026 Valencia, Spain
Interests: nutrition; medicinal plants; natural products; human health; bioactive compounds
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Special Issue Information

Dear Colleagues,

Nowadays, obesity is a pandemic that increases the risk of several chronic diseases, such as diabetes mellitus and cardiovascular and cerebrovascular disease, among others, affecting the quality of life and leading to psychological problems. Weight loss appears to be the most effective therapy for obesity and obesity-related comorbidity. However, several treatments (called magic or miracle diets) might have led to the death of a patient, meaning that it is important for people seeking to lose weight to be followed by a nutrition professional until the individual reaches a desirable body weight. Furthermore, the application of a multidisciplinary focus on slimming diets helps to increase the efficacy of the treatment.

In this Special Issue, we welcome reviews and original articles related to any aspect of obesity and weight loss treatments, from the historical and cultural viewpoints of slimming diets to different weight loss treatments and new advances in the nutrigenomics, the microbiome, and gene–environment interactions in obesity patients. 

Prof. Dr. Jose M. Soriano
Guest Editor

Manuscript Submission Information

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Keywords

  • obesity
  • weight loss treatment
  • dietary supplements
  • anthropometry
  • slimming diets
  • history of weight loss treatments
  • cultural aspect of obesity
  • body composition changes
  • nutrigenomics
  • microbiome
  • gene–environment interactions
  • biomarkers
  • new technology in the weight loss treatment

Published Papers (1 paper)

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Research

13 pages, 9358 KiB  
Article
The Acute Effect of Hydroxychloroquine Sulfate on Hunger, the Plasma Concentration of Orexigenic Peptides and Hedonic Food Intake: A Pilot Study
by Emily Ruilova Sosoranga, Wout Verbeure, Hannelore Geysen, Theo Thijs, Christophe Matthys, Inge Depoortere and Jan Tack
Nutrients 2023, 15(19), 4264; https://doi.org/10.3390/nu15194264 - 05 Oct 2023
Viewed by 1114
Abstract
The direct infusion of bitter solutions in the gastrointestinal tract can reduce the secretion of orexigenic hormones and influence appetite and food intake. We aimed to explore whether oral ingestion of the bitter tastant hydroxychloroquine sulfate can exert similar effects. Ten lean adult [...] Read more.
The direct infusion of bitter solutions in the gastrointestinal tract can reduce the secretion of orexigenic hormones and influence appetite and food intake. We aimed to explore whether oral ingestion of the bitter tastant hydroxychloroquine sulfate can exert similar effects. Ten lean adult women were included in this double-blind, randomized, two-visit, crossover study. After an overnight fast, each volunteer received film-coated tablets containing 400 mg of hydroxychloroquine sulfate (Plaquenil®) or placebo. Plasma-ghrelin, -motilin, -insulin and blood-glucose concentrations were determined every 10 min before and 30 min after feeding; appetite was scored every 10 min. Hunger scores were investigated with a special interest 50–60 min after the ingestion of hydroxychloroquine sulfate, right before a rewarding chocolate milkshake was offered to drink ad libitum. Compared with the placebo, hydroxychloroquine sulfate tended to reduce hunger at the time of interest (p = 0.10). No effect was found upon subsequent milkshake intake. Motilin plasma concentrations were unaltered, but acyl-ghrelin plasma concentrations decreased after the ingestion of hydroxychloroquine sulfate (t = 40–50; p < 0.05). These data suggest that the oral intake of hydroxychloroquine sulfate tablets reduces subjective hunger via a ghrelin-dependent mechanism but does not affect motilin release, hedonic food intake or insulin levels in healthy women. Full article
(This article belongs to the Special Issue Dietary Supplements in Obesity and Weight Loss Treatments)
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