New Trends in Nutritional Therapy for Antiaging Management

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 5 May 2024 | Viewed by 6733

Special Issue Editors


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Department of Pharmaceutical Physics and Informatics, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania
Interests: pharmaceutics and pharmaceutical technology; pharmaceutical research and development; dosage form development; pharmaceutical industry; pharmaceutical analysis; preformulation studiesthree-dimensional printing
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“Ilie Murgulescu” Institute of Physical Chemistry, Romanian Academy, 202 Splaiul Independentei St., 060021 Bucharest, Romania
Interests: physical chemistry, physico-chemical characterization of materials; drug delivery; pharmaceuticals development; thermal analysis; kinetics; biopolymers, cyclodextrin inclusion complexes; hydrogels; biomaterials for biomedical applications; oxide materials design/synthesis and the thermoreactivity of precursor-oxide transformations; green chemistry; thermal properties; physicochemical characterization; nanomaterials for biomedicine; nanomaterials for energy applications; catalysis
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Special Issue Information

Dear Colleagues,

Anti-aging therapies aim to delay (or even reverse) the cellular aging process, in order to increase not only lifespan, but especially the age at which the first chronic diseases appear. The key objectives of anti-aging therapies are as follows: reducing the level of free radicals, fighting inflammation, detoxifying the body, strengthening immunity, eliminating senescent cells, and improving cellular functions (mitochondrial respiration, metabolism, etc.). Unfortunately, increasing the lifespan in the context of a problematic lifestyle has not brought more happiness—the result has been quite the opposite. The appearance of chronic disease at an early age leads to a decrease in the quality of life and to disabilities that can make life a continuous struggle with the disease. In this context, the goal of anti-aging interventions is to delay preclinical aging (i.e., cellular aging), so that the disease is as short as possible in a person's life, until the time when his biological clock stops.

Nutrition is an essential element in maintaining optimal health, and is also a factor that can significantly influence the aging process. Anti-aging therapy emphasizes the use of an adequate diet that counteracts the effect of free radicals, ensures optimal detoxification of the body, reduces inflammatory processes, strengthens the immune system, provides essential nutrients for stimulating regenerative processes, and prevents caloric excess.

Modern nutritional theories are based on nutritional genetics, which studies the molecular genetic mechanisms through which diet predisposes to chronic diseases and premature aging through its two branches: nutrigenetics and nutrigenomics.

Nutrigenetics focuses on the study of how individual genetic characteristics affect the response to nutrients (the relationship between genes and nutrition, individual metabolism, living environment and individual predispositions), thus having an important role in determining the personalized nutritional regime.

Nutrigenomics studies the effect of food and food constituents on gene expression, establishing the correlation between gene expression and the absorption, metabolism, elimination and biological effects of nutrients, having an important role in establishing personalized nutrition according to genotype.

This Special Issue will also focus on the structure–property relationships of food constituents are necessary to establish a correlation between nutrition, foods, or supplements and life quality.

In this Special Issue, theoretical and experimental contributions in the form of full-length original research articles, literature reviews, and short communications are kindly welcome.

We welcome and look forward to your submissions.

Dr. Magdalena Mititelu
Prof. Dr. Doina Drǎgǎnescu
Dr. Adina Magdalena Musuc
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • functional foods
  • cellular regeneration
  • immunoprotection
  • anti-inflammatory nutrition
  • alkalizing nutrition
  • neuroprotective
  • combating oxidative stress
  • detoxifying food
  • nutrigenetics
  • nutrigenomics
  • healthy lifespan extension
  • natural products
  • antiaging agents
  • bioactive compounds
  • physico-chemical characterization

Published Papers (2 papers)

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Research

15 pages, 1488 KiB  
Article
Anti-Wrinkle and Skin Moisture Efficacy of 7-MEGATM: A Randomized, Double-Blind, Placebo Comparative Clinical Trial
by Hyun Kyung Sung, Tae Jeong Kim, Hyung Mook Kim, Sang Jun Youn, Yong Choi, Na Young Lee, Hyun Jeong Oh, Hyuck Se Kwon and Seon Mi Shin
Nutrients 2024, 16(2), 212; https://doi.org/10.3390/nu16020212 - 09 Jan 2024
Viewed by 1707
Abstract
7-MEGATM is a food product made from purified Alaska pollack fish oil containing palmitoleic acid (16:1), commonly referred to as omega-7. We sought to quantitatively evaluate whether this substance inhibits skin aging. A total of 101 middle-aged females were randomly allocated to [...] Read more.
7-MEGATM is a food product made from purified Alaska pollack fish oil containing palmitoleic acid (16:1), commonly referred to as omega-7. We sought to quantitatively evaluate whether this substance inhibits skin aging. A total of 101 middle-aged females were randomly allocated to the intervention (N = 50) or placebo group (N = 51). Each participant was advised to take either 500 mg of 7-MEGATM or a placebo twice daily for 12 weeks. The primary outcomes were the degree of improvement in wrinkles and the degree of moisture filling after consumption for 12 weeks compared to baseline. The secondary outcomes were improvement in skin wrinkles; moisture changes at 4 and 8 weeks from baseline; changes in transdermal water loss, skin elasticity, the melanin index, the erythema index, and the Global Photo Damage Score. We found a significant improvement in skin wrinkles and elasticity at 12 weeks in the 7-MEGATM-consuming group compared to that in the placebo group; skin moisture, elasticity, and the melanin index were also improved. No supplement-related adverse reactions were observed and 7-MEGATM was identified as safe. 7-MEGATM was effective for human skin function in terms of wrinkles, moisture, elasticity, and melanin production and may be useful as a skin nutritional supplement. Full article
(This article belongs to the Special Issue New Trends in Nutritional Therapy for Antiaging Management)
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23 pages, 6671 KiB  
Article
Evaluation of Junk Food Consumption and the Risk Related to Consumer Health among the Romanian Population
by Magdalena Mititelu, Carmen-Nicoleta Oancea, Sorinel Marius Neacșu, Adina Magdalena Musuc, Theodora Claudia Gheonea, Tiberius Iustinian Stanciu, Ion Rogoveanu, Fallah Hashemi, Gabriela Stanciu, Corina-Bianca Ioniță-Mîndrican, Ionela Belu, Nicoleta Măru, Gabriel Olteanu, Alexandru-Tiberiu Cîrțu, Iuliana Stoicescu and Carmen Elena Lupu
Nutrients 2023, 15(16), 3591; https://doi.org/10.3390/nu15163591 - 16 Aug 2023
Cited by 3 | Viewed by 4238
Abstract
Premature aging and degradative processes are mainly generated by unhealthy habits and an unbalanced diet. Quality of food and lifestyle are important factors in sano-genesis. Many imbalances and ailments have their origin in the adoption of an unbalanced diet and a disordered lifestyle. [...] Read more.
Premature aging and degradative processes are mainly generated by unhealthy habits and an unbalanced diet. Quality of food and lifestyle are important factors in sano-genesis. Many imbalances and ailments have their origin in the adoption of an unbalanced diet and a disordered lifestyle. With the help of a transversal study carried out on the basis of a questionnaire, the consumption of junk food products among the population of Romania was evaluated; at the same time, an evaluation of the characteristics of the associated diet, as well as a series of lifestyle components (quality of rest, physical activity, evaluation of the state of health) was carried out. The data collected and processed indicate an increased tendency to consume junk food products in the 18–23 age group, and especially among obese respondents. Female respondents show a lower tendency toward an increased consumption of junk food products (OR = 0.703, 95% CI)—0.19–0.95, p = 0.011) compared to male respondents. The most consumed junk food products are fried potatoes (46.2%) and pastries (41.4%). Junk food products that show an increased tendency toward consumption addiction are fried potatoes (13.8%), sweets (12.4%), pastry products (11.1%), and sweetened drinks (11.2%). The poor quality of food from a nutritional point of view, and reduced physical activity, are reflected in the varied range of problems faced by the respondents: states of fatigue (62.4%), nervousness (37.5%), depression, anxiety, emotional eating, etc. Full article
(This article belongs to the Special Issue New Trends in Nutritional Therapy for Antiaging Management)
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