NeuroSci Journal Club: Highlights on Recent Papers
A topical collection in NeuroSci (ISSN 2673-4087).
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Editors
Prof. Dr. Lucilla Parnetti
Prof. Dr. Lucilla Parnetti
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Collection Editor
Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy
Interests: Alzheimer disease; Parkinson disease; early diagnosis; cerebrospinal fluid biomarkers; alpha synuclein
Special Issues, Collections and Topics in MDPI journals
Topical Collection Information
Dear Colleagues,
The number of papers concerned with neurology and neuroscience published in recent years has exploded. A simple search for ‘neuron’ in WOS on October 2022 yielded 417883 results, over 60% of which were published in the last 10 years. Every researcher in this field knows that there are opportunities to learn and discover new ideas, new concepts, or new tools from studies made in models beyond lab or clinical ones.
Scholars are invited to publish here their research highlights. With this Topical Collection, we aim to collect a selection of the most interesting papers published recently in the neuroscience field. We hope to encourage your curiosity and urge you to read full papers outside of your research area that you may not have read otherwise.
Prof. Dr. Lucilla Parnetti
Dr. Federico Paolini Paoletti
Collection Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. NeuroSci is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript.
The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs).
Submitted papers should be well formatted and use good English. Authors may use MDPI's
English editing service prior to publication or during author revisions.
Published Papers (1 paper)
2022
Open AccessReview
Current Opinion on the Use of c-Fos in Neuroscience
by
Sandra Yasbeth Lara Aparicio, Ángel de Jesús Laureani Fierro, Gonzalo Emiliano Aranda Abreu, Rebeca Toledo Cárdenas, Luis Isauro García Hernández, Genaro Alfonso Coria Ávila, Fausto Rojas Durán, María Elena Hernández Aguilar, Jorge Manzo Denes, Lizbeth Donají Chi-Castañeda and César Antonio Pérez Estudillo
Cited by 14 | Viewed by 11622
Abstract
For years, the biochemical processes that are triggered by harmful and non-harmful stimuli at the central nervous system level have been extensively studied by the scientific community through numerous techniques and animal models. For example, one of these techniques is the use of
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For years, the biochemical processes that are triggered by harmful and non-harmful stimuli at the central nervous system level have been extensively studied by the scientific community through numerous techniques and animal models. For example, one of these techniques is the use of immediate expression genes, which is a useful, accessible, and reliable method for observing and quantifying cell activation. It has been shown that both the
c-fos gene and its protein c-Fos have rapid activation after stimulus, with the length of time that they remain active depending on the type of stimulus and the activation time depending on the stimulus and the structure studied. Fos requires the participation of other genes (such as
c-jun) for its expression (during hetero-dimer forming). c-Fos dimerizes with c-Jun protein to form factor AP-1, which promotes the transcription of various genes. The production and removal of c-Fos is part of cellular homeostasis, but its overexpression results in increased cell proliferation. Although Fos has been used as a marker of cellular activity since the 1990s, which molecular mechanism participates in the regulation of the expression of this protein is still unknown because the gene and the protein are not specific to neurons or glial cells. For these reasons, this work has the objective of gathering information about this protein and its use in neuroscience.
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