Special Issue "Neuroinflammation in Ischemic Stroke"

A special issue of NeuroSci (ISSN 2673-4087).

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 797

Special Issue Editor

Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL 32611, USA
Interests: cerebral ischemia; oxidative stress; neuroinflammation; blood-brain barrier
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Globally, ischemic stroke is one of most common causes of death and long-term disability in adults. Tissue plasminogen activator (tPA) is the only therapeutic agent approved to treat patients with acute ischemic stroke, but it has a very narrow treatment window (<4.5 hours). Ischemic stroke can be complicated by disruption of the blood-brain barrier (BBB) leading to cerebral edema, which contributes significantly to neuronal death and mortality. Injury to the BBB is largely due to an increase of neuroinflammation in ischemic brain. Thus, it is of importance to determine the role of neuroinflammation in ischemic stroke. We are pleased to invite you contributing any research work concerning with special attention to influences of immune cells, inflammatory cytokines and chemokines, oxidative stress, matrix metalloproteinases (MMPs), and other inflammation related pathological mediators in ischemic brain tissue damage and repair. This special issue aims to understand the role of inflammatory mediators in ischemic brain, which could help develop novel diagnostic, prognostic and therapeutic strategies for stroke patients. In this issue, original research articles, reviews and short communication are welcome, and manuscripts describing novel techniques or methods to reduce stroke injury are also considered.

We sincerely look forward to receiving your contributions.

You may choose our Joint Special Issue in Biomolecules.   

Dr. Changjun Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. NeuroSci is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cerebral ischemia
  • focal ischemic injury
  • neuroinflammation
  • oxidative stress
  • blood-brain barrier
  • neurovascular unit
  • tight junction proteins

Published Papers

There is no accepted submissions to this special issue at this moment.
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