Special Issue "Roles of Non-coding RNAs in Drug Metabolism and Disposition"

A special issue of Non-Coding RNA (ISSN 2311-553X).

Deadline for manuscript submissions: 15 March 2024 | Viewed by 173

Special Issue Editors

Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, 69 N Eagleville Road, Storrs, CT 06269, USA
Interests: P450-mediated drug metabolism; drug-induced liver injury; epigenetics; lncRNAs; nucleic acid therapeutics; ASOs; siRNAs
Prof. Dr. Lirong Zhang
E-Mail Website
Guest Editor
Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China
Interests: epigenetics; non-coding RNAs; nuclear receptors; ontogeny of drug-metabolizing enzymes

Special Issue Information

Dear Colleagues,

Drug metabolism and disposition are biological processes that occur after drugs are administrated into the body, including absorption, distribution, metabolism, and excretion (ADME), which have direct impacts on the therapeutic efficacy and toxicity of drugs. Drug-metabolizing enzymes and transporters are major key players in determining the features of ADME of small chemical drugs, which are tightly regulated by various key regulatory factors, including non-coding RNAs (ncRNAs). Accumulated evidence has shown that microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) participate in regulatory events at various levels of transcription, post-transcription, and translation to control expression of drug-metabolizing enzymes and transporters at the key drug-processing organs, such as the liver, intestine, and kidneys. This Special Issue aims to publish a set of research and review articles focusing on the emerging knowledge of the roles of ncRNAs in drug metabolism and disposition.

Prof. Dr. Xiaobo Zhong
Prof. Dr. Lirong Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • ncRNAs
  • lncRNAs
  • miRNAs
  • drug metabolizing enzymes
  • transporters

Published Papers

This special issue is now open for submission.
Back to TopTop