Nanomaterials: Recent Advances in Biomedical and Sensing Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (6 June 2023) | Viewed by 1749

Special Issue Editors


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Guest Editor
College of Arts and Sciences, Cleveland State University, Cleveland, OH, USA
Interests: functional biomaterials; antithrombotic surfaces; biomimetic interfaces; electron-transfer; nitric oxide synthases; metalloproteins; metalloenzymes; DNA-sensors; DNA-protein interaction; oxidative stress metabolite sensors; disease marker detection; nanotechnology; nanostructured interfaces
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Guest Editor
National Research Centre, Cairo, Egypt
Interests: computational physics; quantum mechanics; ab initio; molecular structure; hydrogen bonding; calculations; density functional theory; fullerenes; protease inhibitors; electronic structure; QSAR; molecular modeling

Special Issue Information

Dear Colleagues,

This Special Issue invites the submission of original research papers and review articles on recent advances in nanomaterials, including nanostructured films. All aspects of their unique properties, including their optical, electrical, thermal, mechanical, and biological characteristics, and their applications in sensing, biology, optical devices, and imaging will be covered in this Special Issue. We welcome reviews, viewpoints, and original research papers that pique readers’ interest in nanoscale biomedical applications. The extremely rapid development of nanostructured devices and/or materials and the new frontiers that their capabilities open both illustrate the need for a focused Special Issue. Topics of interest include, but are not limited to, nanostructures, nanofilms, nanointerfaces, nanomaterials, nanocomposites, as well as nanotubes and nanosheets, and all aspects of their application.

Dr. Mekki Bayachou
Dr. Medhat A. Ibrahim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanopartcles
  • nanostructured materials
  • oxidative stress markers
  • biosensors and biosensor design
  • biological applications oxidative stress
  • nanomaterial interfaces
  • reactive oxygen species
  • anticancer
  • drug design
  • biomedical applications
  • molecular biology
  • nanotechnology

Published Papers (1 paper)

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Research

12 pages, 1870 KiB  
Article
Microspheres with 2D rGO/Alginate Matrix for Unusual Prolonged Release of Cefotaxime
by Islam Gomaa, Merna H. Emam, Ahmed R. Wassel, Kholoud Ashraf, Sara Hussan, Haitham Kalil, Mekki Bayachou and Medhat A. Ibrahim
Nanomaterials 2023, 13(9), 1527; https://doi.org/10.3390/nano13091527 - 01 May 2023
Cited by 2 | Viewed by 1474
Abstract
A synergistic interaction between reduced graphene oxide (rGO) and a biodegradable natural polymer, sodium alginate, was developed to create unique microspheres with protruding spiky features at the surface (spiky microspheres) that act as a super encapsulation and sustained release system for the highly [...] Read more.
A synergistic interaction between reduced graphene oxide (rGO) and a biodegradable natural polymer, sodium alginate, was developed to create unique microspheres with protruding spiky features at the surface (spiky microspheres) that act as a super encapsulation and sustained release system for the highly effective antibiotic cefotaxime. Three forms of microspheres, namely alginate (Alg), alginate-cefotaxime (Alg-CTX), and alginate-cefotaxime-reduced graphene (Alg-CTX-rGO) composites, were prepared using calcium chloride as a cross-linking agent. The microspheres were characterized using field emission scanning electron microscopy (FESEM), Fourier-transform infrared (FT-IR) spectroscopy, and X-ray diffraction to investigate their pores, roughness, surface morphology, functional groups, phase formation, purity, and structural properties. The membrane diffusion method was employed to determine the release profile of Cefotaxime from the fabricated microspheres. The antibacterial activities of CTX solution, Alg microspheres, Alg-CTX microspheres, and Alg-CTX-rGO microspheres were investigated against gram-negative bacteria (Escherichia coli) using the agar diffusion method on Muller–Hinton agar. The prepared samples exhibited excellent results, suggesting their potential for enhanced antibiotic delivery. The results demonstrated the potential of the microsphere 2D rGO/alginate matrix for enhancing cefotaxime delivery with an unusual, prolonged release profile. Full article
(This article belongs to the Special Issue Nanomaterials: Recent Advances in Biomedical and Sensing Applications)
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