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Towards Sustainable Solutions: Recent Advances in Polyphenol-Based Biomaterials

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2648

Special Issue Editor


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Guest Editor
1. MED–Mediterranean Institute for Agriculture, Environment and Development, University of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, Ed. 8, 8005-139 Faro, Portugal
2. FSCN, Surface and Colloid Engineering, Mid Sweden University, SE-851 70 Sundsvall, Sweden
Interests: rheology; biopolymers; biomaterials; colloids; lignocellulose; polyphenol dissolution and extraction
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Special Issue Information

Dear Colleagues,

Natural polyphenols represent a class of polyphenolic compounds extensively present in living species ranging from bacteria and fungi up to plants to animals. These biomolecules play several key roles, such as cytoprotection, iron transport, pigmentation, metal coordination, and signal transmission, among others. Interestingly, natural polyphenols have been reported with remarkable functional properties, such as antibacterial, anticancer, anti-inflammatory, antioxidant, anti-metastatic, antiviral, anthelmintic, β-amyloid inhibition, myocardial protection, and immune-regulatory activities. Due to these multipurpose properties, natural polyphenols have been attracting growing interest in diverse areas from food and cosmetics up to pharmaceutics and medicine. This Special Issue intends to cover the most recent fundamental (e.g., extraction, characterization, self-assembly and interactions with other molecules, mechanisms of action) and applied aspects (e.g., strategies to develop and characterize novel engineered natural polyphenol-based nanoparticles, drug delivery systems, films, hydrogels, composites, foams).

Dr. Bruno Medronho
Guest Editor

Manuscript Submission Information

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Keywords

  • natural polyphenols
  • extraction and characterization
  • biomaterials
  • functional properties

Published Papers (1 paper)

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Research

12 pages, 2250 KiB  
Article
On the Development of Phenol-Formaldehyde Resins Using a New Type of Lignin Extracted from Pine Wood with a Levulinic-Acid Based Solvent
by Elodie Melro, Filipe E. Antunes, Artur J. M. Valente, Hugo Duarte, Anabela Romano and Bruno Medronho
Molecules 2022, 27(9), 2825; https://doi.org/10.3390/molecules27092825 - 29 Apr 2022
Cited by 9 | Viewed by 1992
Abstract
Resole resins have many applications, especially for foam production. However, the use of phenol, a key ingredient in resoles, has serious environmental and economic disadvantages. In this work, lignin extracted from pine wood using a “green” solvent, levulinic acid, was used to partially [...] Read more.
Resole resins have many applications, especially for foam production. However, the use of phenol, a key ingredient in resoles, has serious environmental and economic disadvantages. In this work, lignin extracted from pine wood using a “green” solvent, levulinic acid, was used to partially replace the non-sustainable phenol. The physicochemical properties of this novel resin were compared with resins composed of different types of commercial lignins. All resins were optimized to keep their free formaldehyde content below 1 wt%, by carefully adjusting the pH of the mixture. Substitution of phenol with lignin generally increases the viscosity of the resins, which is further increased with the lignin mass fraction. The addition of lignin decreases the kinetics of gelification of the resin. The type and amount of lignin also affect the thermal stability of the resins. It was possible to obtain resins with higher thermal stability than the standard phenol-formaldehyde resins without lignin. This work provides new insights regarding the development of lignin-based resoles as a very promising sustainable alternative to petrol-based resins. Full article
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