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Characterization, Analysis and Application of Natural Antioxidants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 3804

Special Issue Editors


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Guest Editor
Department of Chemistry, Faculty of Science, Istanbul University, 34126 Istanbul, Turkey
Interests: analytical method development for antioxidants and other food constituents; optical sensors; nanosensors; food chemistry; natural products chemistry; phytochemicals; antioxidants
Special Issues, Collections and Topics in MDPI journals
School of Nutrition and Food Sciences, Louisiana State University, Baton Rouge, LA 70803, USA
Interests: phytochemicals; antioxidants; flavor; lipids; liquid chromatography; gas chromatography

Special Issue Information

Dear Colleagues,

The consumption of natural antioxidants is considered one of the important ways to combat serious health risks arising from “oxidative stress” conditions, and interest in these types of antioxidants has increased significantly in recent years. Research has focused on the study of the individual or collective extraction, isolation, characterization, and analysis of these natural antioxidants from natural sources such as fruits, vegetables, herbs, and spices. In addition, huge amounts of waste and by-products are produced throughout the agri-food supply chain, and many studies on the recovery of antioxidants from these by-products are at the forefront.

The scope of this Special Issue titled “Characterization, Analysis and Application of Natural Antioxidants” includes the isolation and characterization of antioxidants from all kinds of natural sources, antioxidant capacity/activity evaluations, the examination of other important quality parameters, and the development of new analytical methods for natural antioxidants. In addition, this Special Issue covers various applications of natural antioxidants and new approaches to the valorization of agricultural wastes.

Dr. Mustafa Bener
Dr. Zhimin Xu
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • natural sources
  • valorization of agricultural wastes
  • analysis of natural antioxidants
  • analytical methods for antioxidants
  • characterization of natural antioxidants
  • application of natural antioxidants

Published Papers (2 papers)

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Research

13 pages, 1661 KiB  
Article
Flavanones from Erythrina crista-galli Twigs and Their Antioxidant Properties Determined through In Silico and In Vitro Studies
by Vanny Deviani, Ari Hardianto, Kindi Farabi and Tati Herlina
Molecules 2022, 27(18), 6018; https://doi.org/10.3390/molecules27186018 - 15 Sep 2022
Cited by 3 | Viewed by 1487
Abstract
Flavonoids are a secondary metabolite group with various bioactivities, such as antioxidants. They are rich in the genus Erythrina, such as Erythrina crista-galli. This research aims to isolate and characterize flavonoids from the twigs of E. crista-galli and determine their antioxidant [...] Read more.
Flavonoids are a secondary metabolite group with various bioactivities, such as antioxidants. They are rich in the genus Erythrina, such as Erythrina crista-galli. This research aims to isolate and characterize flavonoids from the twigs of E. crista-galli and determine their antioxidant properties through in silico and in vitro assays. The ethyl acetate extract of E. crista-galli twigs were separated by column chromatography and characterized using spectroscopic methods. Density functional theory (DFT) calculations were performed on the isolated flavonoids and the reference compounds (ascorbic acid and quercetin) to obtain global descriptive parameters and a donor–acceptor map (DAM). We successfully isolated lupinifolin (1) and citflavanone (2) for the first time from E. crista-galli, along with lonchocarpol A (3), which has been discovered previously. The DAM suggests that these flavanones are good antiradicals with effective electron donors. However, they tend to be electron acceptors in methanol. The frontier molecular orbital analysis implies that lupinifolin (1) is a better antiradical than the other flavanones. The DPPH assays show that lupinifolin (1) has the highest antioxidant (antiradical) activity, with an IC50 value of 128.64 ppm. The in silico studies showed similar trends to the in vitro assays using the DPPH method. Full article
(This article belongs to the Special Issue Characterization, Analysis and Application of Natural Antioxidants)
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16 pages, 1562 KiB  
Article
Optimized Green Extraction of Polyphenols from Cassia javanica L. Petals for Their Application in Sunflower Oil: Anticancer and Antioxidant Properties
by Mohamed Ibrahim Younis, Xiaofeng Ren, Azalldeen Kazal Alzubaidi, Khaled Fahmy Mahmoud, Ammar B. Altemimi, Francesco Cacciola, Husnain Raza, Anubhav Pratap-Singh and Tarek Gamal Abedelmaksoud
Molecules 2022, 27(14), 4329; https://doi.org/10.3390/molecules27144329 - 06 Jul 2022
Cited by 2 | Viewed by 1685
Abstract
The total phenolic content (TPC) from Cassia javanica L. petals were extracted using ethanolic solvent extraction at concentrations ranging from 0 to 90% and an SCF-CO2 co-solvent at various pressures. Ultrasound-assisted extraction parameters were optimized using response surface methodology (RSM). Antioxidant and [...] Read more.
The total phenolic content (TPC) from Cassia javanica L. petals were extracted using ethanolic solvent extraction at concentrations ranging from 0 to 90% and an SCF-CO2 co-solvent at various pressures. Ultrasound-assisted extraction parameters were optimized using response surface methodology (RSM). Antioxidant and anticancer properties of total phenols were assessed. An SCF-CO2 co-solvent extract was nano-encapsulated and applied to sunflower oil without the addition of an antioxidant. The results indicated that the best treatment for retaining TPC and total flavonoids content (TFC) was SCF-CO2 co-solvent followed by the ultrasound and ethanolic extraction procedures. Additionally, the best antioxidant activity by β-carotene/linoleic acid and DPPH free radical-scavenging test systems was observed by SCF-CO2 co-solvent then ultrasound and ethanolic extraction methods. SCF-CO2 co-solvent recorded the highest inhibition % for PC3 (76.20%) and MCF7 (98.70%) and the lowest IC50 value for PC3 (145 µ/mL) and MCF7 (96 µ/mL). It was discovered that fortifying sunflower oil with SCF-CO2 co-solvent nanoparticles had a beneficial effect on free fatty acids and peroxide levels. The SCF-CO2 method was finally found to be superior and could be used in large-scale processing. Full article
(This article belongs to the Special Issue Characterization, Analysis and Application of Natural Antioxidants)
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