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Technologies for Extraction of Bioactive Compounds from Natural Sources and Their Applications as Cosmeceuticals, Nutraceuticals and Food Ingredients

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 13437

Special Issue Editors

Special Issue Information

Dear Colleagues,

The study of recovering processes to obtain bioactive compounds from natural sources has expanded in the last decade. This interest has been focused on commercial purposes, including cosmetics, dietary supplements, and functional food formulation.

For this reason, a Special Issue in Molecules focused on extraction and chemical characterization of bioactives with potential use as cosmeceuticals, nutraceuticals, and functional food ingredients will provide an overview of the current status and future perspectives on the manufacturing design of these highly valuable products.

Considering your significant research background in the following fields, potential topics include, but are not limited to, the following:

► Bioactive compounds from medicinal plants:

  • Secondary metabolites, • Phenolic compounds, • Terpenes and Terpenoids, • Chemical characterization, • Bioactive properties;

► Bioactive compounds from marine organisms and microorganisms:

  • Secondary metabolites, • Phenolic compounds, • Seagrass, • Seaweeds, • Marine bacteria, • Cyanobacteria, • Microalgae, • Chemical characterization, • Bioactive properties;

► Bioactive compounds from food byproducts:

  • Chemical characterization of food byproducts, • Bioactive properties, • Valorization of food byproducts;

►Sustainable and clean extraction technologies:

  • Green and GRAS solvent, • Supercritical fluid extraction, • Microwave-assisted extraction, • Ultrasound-assisted extraction, • Pressurized liquid extraction, •Enzymatic extraction, • Experimental design;

► Applications as cosmeceuticals, nutraceuticals, and food ingredients:

  • Cosmeceutical applications, • Dietary supplements, • Functional food formulation.

This Special Issue on “Technologies for Extraction of Bioactive Compounds from Natural Sources and Their Applications as Cosmeceuticals, Nutraceuticals, and Food Ingredients” will include a selection of recent research and current review articles about the composition and content of bioactive compounds in natural products. This Special Issue is particularly focused on articles describing new extraction processes to recover bioactive compounds from different sources, comprehensive chemical characterization, bioactive properties, and applications as functional ingredients.

We cordially invite you to contribute original research papers or reviews to this Special Issue of Molecules.


Prof. Jesús Lozano-Sánchez

Prof. Dr. David Arráez-Román
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Bioactive compounds from medicinal plants
  • Bioactive compounds from marine organisms and microorganisms
  • Bioactive compounds from food byproducts
  • Sustainable and clean extraction technologies
  • Applications as cosmeceuticals, nutraceuticals, and food ingredients

Published Papers (2 papers)

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Research

15 pages, 627 KiB  
Article
Extraction Processes with Several Solvents on Total Bioactive Compounds in Different Organs of Three Medicinal Plants
by Nour El Houda Lezoul, Mohamed Belkadi, Fariborz Habibi and Fabián Guillén
Molecules 2020, 25(20), 4672; https://doi.org/10.3390/molecules25204672 - 13 Oct 2020
Cited by 56 | Viewed by 8147
Abstract
The extraction of secondary metabolites by water, MeOH:water (8:2) containing NaF, methanol, ethanol and acetone (all of them diluted (7:3) in water)from the different parts (leaves, flowers, stems and roots) of Passiflora caerulea L., Physalis peruviana L. and Solanum muricatum Aiton via decoction [...] Read more.
The extraction of secondary metabolites by water, MeOH:water (8:2) containing NaF, methanol, ethanol and acetone (all of them diluted (7:3) in water)from the different parts (leaves, flowers, stems and roots) of Passiflora caerulea L., Physalis peruviana L. and Solanum muricatum Aiton via decoction and maceration methods was studied. The highest extraction yields were recorded by methanol for decoction and acetone for maceration. The total polyphenol content (TPC) obtained by decoction had the highest TPC contents, and MeOH containing NaF was the best solvent for the extraction of TPC. Maceration was suitable for flavonoid extractions, with ethanol and acetone being the best solvents. In general, the highest levels of TPC and flavonoids were obtained from Passiflora leaves regardless of the solvent or extraction method applied. Furthermore, the roots of Physalis and Solanum showed important levels of these compounds in consonance with the total antioxidant activity (TAA) evaluated in the different organs of the plant in the three species. In this study, the solvents and extraction methods applied were tools that determined significantly the level of extraction of bioactive compounds, showing a different impact on plant organs for each medicinal species studied. Full article
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27 pages, 2726 KiB  
Article
Effect of Experimental Parameters on the Extraction of Grape Seed Oil Obtained by Low Pressure and Supercritical Fluid Extraction
by Rita de Cássia de Souza, Bruna Aparecida Souza Machado, Gabriele de Abreu Barreto, Ingrid Lessa Leal, Jeancarlo Pereira dos Anjos and Marcelo Andrés Umsza-Guez
Molecules 2020, 25(7), 1634; https://doi.org/10.3390/molecules25071634 - 02 Apr 2020
Cited by 24 | Viewed by 4546
Abstract
Grape seeds are an important byproduct from the grape process. The objective of this work was to evaluate the effect of experimental parameters (temperature and time of pretreatment with ultrasound) to obtain grape seed oil using low pressure (Soxhlet-Sox and Bligh Dyer-BD) and [...] Read more.
Grape seeds are an important byproduct from the grape process. The objective of this work was to evaluate the effect of experimental parameters (temperature and time of pretreatment with ultrasound) to obtain grape seed oil using low pressure (Soxhlet-Sox and Bligh Dyer-BD) and high pressure (supercritical carbon dioxide-SFE) methods. The best condition for pretreatment of samples was 30 min of sonication at 30 °C before extraction by Sox or BD. Ultrasound pretreatment was efficient to increase oil extraction yield by 32.10 (Sox), 20.31 (BD) and 12.54% (SFE), depending on the extraction method used as well as, and certainly influenced the total phenolic concentration in 311 (Sox), 234 (BD), and 184 (SFE)%. Ten fatty acids were identified in the oils, the major ones being 18:2ω-6cis (linoleic 52.39%–63.12%), 16:0 (palmitic 20.22%–26.80%) and 18:0 (stearic 8.52%–13.68%). The highest epicatechin concentration was identified in the BD sample: 30-30 (150.49 ± 5.98mg/kg), which presented a concentration of ≥3 times compared to the control (56.68 ± 1.81mg/kg). Ultrasound pretreatment also contributed positively (56% and 99% increase) in the α-tocopherol content of the SFE: 30-30 and BD: 30-30 samples, respectively. The results indicate that the ultrasound pretreatment is a suitable technology to improve the quality of the oil from the grape seed. Full article
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