Understanding the Impact of Reactive Coatings to Create Multi-Functional Surfaces in Polymeric Scaffolds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".
Deadline for manuscript submissions: closed (30 August 2021) | Viewed by 430
Special Issue Editors
Interests: biomaterials; hydrogels tissue engineering; stem cell biology; scaffolds; polydopamine; polysaccharides; nanocomposite materials; drug delivery
Interests: on demand (AMF or PEMF and nsPEF as trigger) controlled release from responsive liposomes; hybrid gel-in-liposomes as a new tool for drug delivery; cyclodextrins; controlled release from polymeric materials for pharmaceutical use
Special Issues, Collections and Topics in MDPI journals
Interests: hydrogels; drug delivery; composite systems; polysaccharides; rheomechanical properties of hydrogels; micro- and nanoparticulate delivery systems
Special Issues, Collections and Topics in MDPI journals
Interests: hydrogels; drug delivery; composite systems; polysaccharides; rheomechanical properties of hydrogels; micro and nanoparticulate delivery systems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The use of polymeric reactive coatings for biomaterial-based scaffolds has been largely used as a strategy to bind different types of drugs and biomolecules. One of the most successful polymers is represented by polydopamine (pDA), which is cheap, effective, and does not require elaborate steps for its deposition. pDA’s unique chemical structure enables conjugation with a variety of peptides, growth factors, and other biological molecules, expanding the biological potential of many inert surfaces. However, pDA is not the only biomaterial to have this potential effect. Nature offers a great variety of designs and polymeric solutions to create reactive adhesive interfaces with defined surface properties. Identifying these new biomaterials and studying their chemical properties could be the key to expanding the available strategies necessary to obtain new interfaces for scaffolds used in biomedical applications.
Therefore, this Special Issue is open to original submissions, including manuscripts, reviews, and short communications that address this topic according to the keywords reported below. The goal of this collection is to identify or synthesize novel reactive polymeric layers and investigate their impact on the surface properties of biomedical scaffolds. Studies reporting a direct comparison in the chemical reactivity of pDA-based coatings with other types of natural or synthetic binding coatings will also be accepted. Finally, this Special issue will welcome contributions highlighting the use of these reactive polymeric layers to bind several biological molecules, including but not limited to biomimetic peptides, growth factors, and small drugs.
Dr. Settimio Pacelli
Dr. Stefania Petralito
Prof. Dr. Patrizia Paolicelli
Prof. Dr. Maria Antonietta Casadei
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Reactive layer fabrication strategies
- Polymeric coatings
- Scaffold design
- Surface characterization
- Mechanical characterization
- Interface properties
- Proteins, peptides, and drug conjugation
- Chemical characterization
- Adsorption and desorption processes
- pDA layer characterization and comparison
