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Molecules
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Plant Sourced Compounds: Extraction, Identification and Bioactivity
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Plant Sourced Compounds: Extraction, Identification and Bioactivity

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 2135

Special Issue Editors

Dr. Md Saifullah

E-Mail Website
Guest Editor
Tasmanian institute of agriculture, University of Tasmania, Launceston, Australia
Interests: extraction; optimization; bioactive compound; microencapsulation; novel antioxidant
Dr. Quan V. Vuong

E-Mail Website
Guest Editor
Food Science, School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, Australia
Interests: functional food; bioactive compounds in food; waste utilization; antioxidant; extraction; microencapsulation
Special Issues, Collections and Topics in MDPI journals
Dr. Mohammad Rezaul Islam Shishir

E-Mail Website
Guest Editor
Institute for Advanced Study, Shenzhen University, Shenzhen, China
Interests: bioactive food compounds, micro- and nanoencapsulation; drug delivery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plant-derived phytochemicals are linked to various health benefits; thus, they have been widely used in the nutraceutical, cosmetic and pharmaceutical industries. However, phytochemicals are diverse, with various structures, compositions and plant material properties. Therefore, it is important to ensure the cost-effective extraction, identification and testing of the bioactivities of phytochemicals derived from plants for the development of further applications. Numerous factors affect the extractability, stability and properties of phytochemicals during the pre-treatment, extraction and isolation processes. Thus, comprehensive studies are needed to establish the optimal conditions for these procedures. In addition, the identification of unknown compounds and testing of their biological properties are essential to establish further potential uses of phytochemicals as functional ingredients in food, cosmetics, pharmaceuticals or other products. This Special Issue aims to bring together the most recent reviews and research papers related to the pre-treatment, extraction, identification and bioactivity of volatile and non-volatile phytochemicals derived from plants and their potential uses as functional ingredients.

Dr. MD Saifullah
Dr. Quan V. Vuong
Dr. Mohammad Rezaul Islam Shishir
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • extraction
  • optimization
  • identification
  • bioactivity
  • application
  • bioavailability
  • new compound discovery

Published Papers (3 papers)

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Research

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13 pages, 1702 KiB  
Article
The Antioxidant, Anti-Inflammatory and Moisturizing Effects of Camellia oleifera Oil and Its Potential Applications
by Lijun Zhou, Yunlan Peng, Zhou Xu, Jingyi Chen, Ningbo Zhang, Tao Liang, Tao Chen, Yao Xiao, Shiling Feng and Chunbang Ding
Molecules 2024, 29(8), 1864; https://doi.org/10.3390/molecules29081864 - 19 Apr 2024
Viewed by 198
Abstract
Camellia oleifera oil (CO oil) extracted from C. oleifera seeds has a 2300-year consumption history in China. However, there is relatively little research regarding its non-edible uses. This study determined the physicochemical properties of CO oil extracted via direct pressing, identified its main [...] Read more.
Camellia oleifera oil (CO oil) extracted from C. oleifera seeds has a 2300-year consumption history in China. However, there is relatively little research regarding its non-edible uses. This study determined the physicochemical properties of CO oil extracted via direct pressing, identified its main components using GC-MS, and evaluated its antioxidant, moisturizing, and anti-inflammatory activities. The results revealed that CO oil’s acid, peroxide, iodine, and saponification values were 1.06 ± 0.031 mg/g, 0.24 ± 0.01 g/100 g, 65.14 ± 8.22 g/100 g, and 180.41 ± 5.60 mg/g, respectively. CO oil’s tocopherol, polyphenol, and squalene contents were 82.21 ± 9.07 mg/kg, 181.37 ± 3.76 mg/kg, and 53.39 ± 6.58 mg/kg, respectively; its unsaturated fatty acid (UFA) content was 87.44%, and its saturated fatty acid (SFA) content was 12.56%. CO oil also demonstrated excellent moisture retention properties, anti-inflammatory effects, and certain free radical scavenging. A highly stable CO oil emulsion with competent microbiological detection was developed using formulation optimization. Using CO oil in the emulsion significantly improved the formulation’s antioxidant and moisturizing properties compared with those of the emulsion formulation that did not include CO oil. The prepared emulsion was not cytotoxic to cells and could reduce cells’ NO content; therefore, it may have potential nutritional value in medicine and cosmetics. Full article
(This article belongs to the Special Issue Plant Sourced Compounds: Extraction, Identification and Bioactivity)
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Review

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25 pages, 6802 KiB  
Review
Recent Advances in Grayanane Diterpenes: Isolation, Structural Diversity, and Bioactivities from Ericaceae Family (2018–2024)
by Sheng Liu, Lili Sun, Peng Zhang and Changshan Niu
Molecules 2024, 29(7), 1649; https://doi.org/10.3390/molecules29071649 - 06 Apr 2024
Viewed by 574
Abstract
Diterpenes represent one of the most diverse and structurally complex families of natural products. Among the myriad of diterpenoids, grayanane diterpenes are particularly notable. These terpenes are characterized by their unique 5/7/6/5 tetracyclic system and are exclusive to the Ericaceae family of plants. [...] Read more.
Diterpenes represent one of the most diverse and structurally complex families of natural products. Among the myriad of diterpenoids, grayanane diterpenes are particularly notable. These terpenes are characterized by their unique 5/7/6/5 tetracyclic system and are exclusive to the Ericaceae family of plants. Renowned for their complex structures and broad spectrum of bioactivities, grayanane diterpenes have become a primary focus in extensive phytochemical and pharmacological research. Recent studies, spanning from 2018 to January 2024, have reported a series of new grayanane diterpenes with unprecedented carbon skeletons. These compounds exhibit various biological properties, including analgesic, antifeedant, anti-inflammatory, and inhibition of protein tyrosine phosphatase 1B (PTP1B). This paper delves into the discovery of 193 newly identified grayanoids, representing 15 distinct carbon skeletons within the Ericaceae family. The study of grayanane diterpenes is not only a deep dive into the complexities of natural product chemistry but also an investigation into potential therapeutic applications. Their unique structures and diverse biological actions make them promising candidates for drug discovery and medicinal applications. The review encompasses their occurrence, distribution, structural features, and biological activities, providing invaluable insights for future pharmacological explorations and research. Full article
(This article belongs to the Special Issue Plant Sourced Compounds: Extraction, Identification and Bioactivity)
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24 pages, 2091 KiB  
Review
Research Progress on Sesquiterpene Compounds from Artabotrys Plants of Annonaceae
by Yupei Sun, Jianzeng Xin, Yaxi Xu, Xuyan Wang, Feng Zhao, Changshan Niu and Sheng Liu
Molecules 2024, 29(7), 1648; https://doi.org/10.3390/molecules29071648 - 06 Apr 2024
Viewed by 340
Abstract
Artabotrys, a pivotal genus within the Annonaceae family, is renowned for its extensive biological significance and medicinal potential. The genus’s sesquiterpene compounds have attracted considerable interest from the scientific community due to their structural complexity and diverse biological activities. These compounds exhibit [...] Read more.
Artabotrys, a pivotal genus within the Annonaceae family, is renowned for its extensive biological significance and medicinal potential. The genus’s sesquiterpene compounds have attracted considerable interest from the scientific community due to their structural complexity and diverse biological activities. These compounds exhibit a range of biological activities, including antimalarial, antibacterial, anti-inflammatory analgesic, and anti-tumor properties, positioning them as promising candidates for medical applications. This review aims to summarize the current knowledge on the variety, species, and structural characteristics of sesquiterpene compounds isolated from Artabotrys plants. Furthermore, it delves into their pharmacological activities and underlying mechanisms, offering a comprehensive foundation for future research. Full article
(This article belongs to the Special Issue Plant Sourced Compounds: Extraction, Identification and Bioactivity)
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