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The Chemistry of Nitrocompounds 2.0

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (1 February 2024) | Viewed by 1018

Special Issue Editor


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Guest Editor
Dean of Chemistry and Pharmacy Faculty, North Caucasus Federal University, Stavropol, Russia
Interests: directed synthesis; atomic accuracy; molecular complexity; structural diversity; fluorine; heterocyclic system; catalysis; biactivity; nitrocompounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We cordially invite you to contribute original research papers or reviews to this Special Issue of Molecules, the topic of which is purposely defined rather broadly as the chemistry of nitrocompounds. Historically, nitrocompounds have proven to be very versatile synthetic organic chemistry intermediates, both as a means of constructing C-C or C-heteroatom bonds and as a convenient starting point for conversion into many other classes of organic substances.

At present, the ever-increasing use of chemicals bearing nitro groups as perspective materials, pharmaceuticals, agrochemicals etc. encourages research in diverse areas to seek new synthetic methodologies or insights on how the rich chemistry of nitro compounds could be utilized regarding the above-mentioned practical aspects.

Therefore, the main aim of this Special issue is to share these findings and results among fellow scientists. We welcome the submission of papers covering any aspects of nitro group chemistry under a broadly defined condition that present interesting findings in the perspective of fine organic synthesis. We particularly welcome studies on the application of nitro compounds in the preparation of biologically active and natural carbo- and heterocyclic molecules.

Dr. Alexander V. Aksenov
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • new organic synthetic methods
  • nitro group transformations
  • synthesis of heterocycles
  • multicomponent reactions
  • new reagents
  • natural products
  • synthetic/atom efficiency

Published Papers (1 paper)

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Research

11 pages, 2574 KiB  
Article
Reconstructive Methodology in the Synthesis of 2-Aminopurine
by Artyom O. Neymash, Evgeny N. Ulomsky, Victor V. Fedotov, Semen V. Aminov, Daniil N. Lyapustin, Evgeny B. Gorbunov, Vladislav A. Ishimnikov, Pavel A. Slepukhin and Vladimir L. Rusinov
Molecules 2024, 29(1), 134; https://doi.org/10.3390/molecules29010134 - 25 Dec 2023
Viewed by 689
Abstract
A fundamentally new synthetic approach to the synthesis of 2-aminopurine has been developed. It consists in the combination of the creation of a condensed polyazotic heterocyclic tetrazolopyrimidine structure, its transformation into triaminopyrimidine, and its subsequent cyclization into 2-aminopurine. The structure of the obtained [...] Read more.
A fundamentally new synthetic approach to the synthesis of 2-aminopurine has been developed. It consists in the combination of the creation of a condensed polyazotic heterocyclic tetrazolopyrimidine structure, its transformation into triaminopyrimidine, and its subsequent cyclization into 2-aminopurine. The structure of the obtained compounds was established based on spectral characteristics, and the structure of the intermediate compound 5 was established directly by X-ray diffraction analysis. Full article
(This article belongs to the Special Issue The Chemistry of Nitrocompounds 2.0)
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