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Nanotechnology Applications in Nanomedicine: Recent Advances and Prospects

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 6079

Special Issue Editors


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Guest Editor
School of Medicine, Jiangsu University, Zhenjiang 212013, China
Interests: nanomedicine; nano systems; nanomaterials; nano drugs; drug delivery
School of Pharmacy, Xuzhou Medical University, Xuzhou 221000, China
Interests: nanomedicine; disease diagnosis; disease treatment; nano drugs; drug delivery

Special Issue Information

Dear Colleagues,

Nanomedicine, an offshoot of nanotechnology, is defined as the “science that uses nanomaterials to the development of diagnosis, treatment and prevention of specific medical application.” Nanomedicine is one of the most rapidly growing fields of translational medicine, because it offers great opportunities to promote innovations in numerous medical fields, including controlled drug delivery, biomarkers, molecular imaging, biosensing, and so on. Notably, the contributions of nanomedicine are still growing in a more spectacular way, along with the development of nanotechnology. This Special Issue, "Nanotechnology Applications in Nanomedicine: Recent Advances and Prospects", aims to collect and disseminate some of the most significant and recent contributions in the field of nanomedicine.

We welcome the submission of original research articles, short communications and review articles that cover, but are not limited to, the following topics:

  • Functionalized nanosystems for drug delivery.
  • Synthesis, pharmacodynamics and pharmacokinetics of nanodrugs.
  • Nanomaterials for imaging, biosensing and disease diagnosis.
  • Nanomedical devices for regenerative medicine.
  • Bioavailability and toxicology of nanomaterials.

Dr. Haijun Shen
Dr. Jin Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

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13 pages, 5334 KiB  
Article
Synthesis of Green Copper Nanoparticles Using Medicinal Plant Krameria sp. Root Extract and Its Applications
by Shifaa O. Alshammari, Sabry Younis Mahmoud and Eman Saleh Farrag
Molecules 2023, 28(12), 4629; https://doi.org/10.3390/molecules28124629 - 8 Jun 2023
Cited by 5 | Viewed by 4055
Abstract
Nanotechnology is one of the most dynamic research areas and the fastest-growing market. Developing eco-friendly products using available resources to acquire maximum production, better yield, and stability is a great challenge for nanotechnology. In this study, copper nanoparticles (CuNP) were synthesized via the [...] Read more.
Nanotechnology is one of the most dynamic research areas and the fastest-growing market. Developing eco-friendly products using available resources to acquire maximum production, better yield, and stability is a great challenge for nanotechnology. In this study, copper nanoparticles (CuNP) were synthesized via the green method using root extract of the medical plant Rhatany (Krameria sp.) as a reducing and capping agent and used to investigate the influence of microorganisms. The maximum production of CuNP was noted at 70 °C after 3 h of reaction time. The formation of nanoparticles was confirmed through UV-spectrophotometer, and the product showed an absorbance peak in the 422–430 nm range. The functional groups were observed using the FTIR technique, such as isocyanic acid attached to stabilize the nanoparticles. The spherical nature and average crystal sizes of the particle (6.16 nm) were determined using Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and X-ray diffractometer (XRD) analysis. In tests with a few drug-resistant pathogenic bacteria and fungus species, CuNP showed encouraging antimicrobial efficacy. CuNP had a significant antioxidant capacity of 83.81% at 200 g/m−1. Green synthesized CuNP are cost-effective and nontoxic and can be applied in agriculture, biomedical, and other fields. Full article
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Review

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24 pages, 6380 KiB  
Review
Selenium Nanoparticles: A Comprehensive Examination of Synthesis Techniques and Their Diverse Applications in Medical Research and Toxicology Studies
by Shobana Sampath, Veena Sunderam, M. Manjusha, Zodwa Dlamini and Ansel Vishal Lawrance
Molecules 2024, 29(4), 801; https://doi.org/10.3390/molecules29040801 - 9 Feb 2024
Viewed by 1605
Abstract
Selenium is a trace and necessary micronutrient for human, animal, and microbial health. Many researchers have recently been interested in selenium nanoparticles (SeNPs) due to their biocompatibility, bioavailability, and low toxicity. As a result of their greater bioactivity, selenium nanoparticles are widely employed [...] Read more.
Selenium is a trace and necessary micronutrient for human, animal, and microbial health. Many researchers have recently been interested in selenium nanoparticles (SeNPs) due to their biocompatibility, bioavailability, and low toxicity. As a result of their greater bioactivity, selenium nanoparticles are widely employed in a variety of biological applications. Physical, chemical, and biological approaches can all be used to synthesize selenium nanoparticles. Since it uses non-toxic solvents and operates at a suitable temperature, the biological technique is a preferable option. This review article addresses the processes implemented in the synthesis of SeNPs and highlights their medicinal uses, such as the treatment of fungi, bacteria, cancer, and wounds. Furthermore, we discuss the most recent findings on the potential of several biological materials for selenium nanoparticle production. The precursor, extract, process, time, temperature, and other synthesis criteria will be elaborated in conjunction with the product’s physical properties (size, shape, and stability). The synergies of SeNP synthesis via various methods aid future researchers in precisely synthesizing SeNPs and using them in desired applications. Full article
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Liposomes, Dendrimers, and Micelles: Nanoplatforms Revolutionizing Ophthalmic Treatments
Authors: Kevin Yang Wu; Simon D. Tran
Affiliation: Division of Ophthalmology, Department of Surgery, University of Sherbrooke, Sherbrooke, QC J1G 2E8, Canada
Abstract: The eye's complex anatomical structures present formidable barriers to effective drug delivery across a range of ocular diseases, from anterior to posterior segment pathologies. Emerging as a promising solution to these challenges, nanotechnology-based platforms—namely liposomes, dendrimers, and micelles—have shown the potential to revolutionize ophthalmic therapeutics. These nanocarriers enhance drug bioavailability, increase residence time in targeted ocular tissues, and offer precise, localized delivery, minimizing systemic side effects. Liposomes are versatile carriers capable of encapsulating diverse pharmacological agents, lending utility across a spectrum of ocular conditions. Dendrimers allow for highly targeted drug delivery, particularly useful in posterior segment diseases like retinal degenerations. Micelles offer core-shell architectures optimal for drug loading and sustained release. This review, encompassing literature from 2017 to 2023, offers a comprehensive examination of these nanocarriers, elucidating their impact in transforming the treatment landscape for a broad array of ocular diseases. It underscores the necessity for ongoing research to realize their full clinical potential.

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