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Special Issue "Bioactive Compounds in Food: Analysis and Human Health"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 December 2023 | Viewed by 1728

Special Issue Editors

Head of Clinical Nutrition Department, General Hospital Korgialenio Benakio, Athens, Greece
Interests: clinical nutrition; bioactive compounds; lipids; cardiovascular disease
Laboratory of Food Chemistry, Biochemistry and Technology, Department of Food Science and Nutrition, University of the Aegean, 81440 Myrina, Greece
Interests: analysis of food microconstituents; mechanisms of oxidation, thrombosis, and inflammation; health effects of bioactive food microconstituents on chronic inflammatory diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bioactive compounds in foods are usually minor constituents with health effects. They may belong to several categories with differentiated structures such as polyphenols, carotenoids, organosulfur compounds, terpenoids, fatty acids, platelet activating factor (PAF) antagonists, immune-boosting substances, probiotics, prebiotics and others. Nanoparticles being used in the food industry may enhance product features and can also be listed as bioactive compounds. In vitro, animal and human studies have pointed to several health effects of these compounds, such as antioxidant, anti-inflammatory, and anti-thrombotic effects, which in turn render these bioactive compounds as potentially cardioprotective, immune-boosting, anti-diabetic and anti-cancer agents. In the COVID-19 era, such food constituents may contribute to combating infection and possibly affect the clinical course of the disease.

This Special Issue aims to attract original research and review articles describing current findings on the effects of bioactive compounds.

Potential topics include (but are not limited to) the following:

  • Characterization and analysis of bioactive compounds;
  • Potential mechanisms of action of bioactive compounds;
  • Bioactive compounds and oxidative stress;
  • Bioactive compounds and thrombosis;
  • Bioactive compounds and inflammation;
  • Bioactive compounds and cancer;
  • Bioactive compounds and cardiovascular disease;
  • Bioactive compounds and diabetes;
  • Bioactive compounds and hypertension;
  • Bioactive compounds and obesity;
  • Bioactive compounds and COVID-19;
  • Effects of bioactive compounds in ICU;
  • Immune-boosting properties of bioactive compounds;
  • Nanoparticles and health effects;
  • PAF antagonists in foods.

Dr. Paraskevi Detopoulou
Dr. Haralabos Christos Karantonis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • bioactive peptides
  • polyphenols
  • food carotenoids
  • non-nutrients
  • probiotics
  • prebiotics
  • disease
  • nanoparticles

Published Papers (1 paper)

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17 pages, 1237 KiB  
Weight Loss Supplements
Molecules 2023, 28(14), 5357; - 12 Jul 2023
Viewed by 1445
Being overweight or obese can predispose people to chronic diseases and metabolic disorders such as cardiovascular illnesses, diabetes, Alzheimer’s disease, and cancer, which are costly public health problems and leading causes of mortality worldwide. Many people hope to solve this problem by using [...] Read more.
Being overweight or obese can predispose people to chronic diseases and metabolic disorders such as cardiovascular illnesses, diabetes, Alzheimer’s disease, and cancer, which are costly public health problems and leading causes of mortality worldwide. Many people hope to solve this problem by using food supplements, as they can be self-prescribed, contain molecules of natural origin considered to be incapable of causing damage to health, and the only sacrifice they require is economic. The market offers supplements containing food plant-derived molecules (e.g., primary and secondary metabolites, vitamins, and fibers), microbes (probiotics), and microbial-derived fractions (postbiotics). They can control lipid and carbohydrate metabolism, reduce appetite (interacting with the central nervous system) and adipogenesis, influence intestinal microbiota activity, and increase energy expenditure. Unfortunately, the copious choice of products and different legislation on food supplements worldwide can confuse consumers. This review summarizes the activity and toxicity of dietary supplements for weight control to clarify their potentiality and adverse reactions. A lack of research regarding commercially available supplements has been noted. Supplements containing postbiotic moieties are of particular interest. They are easier to store and transport and are safe even for people with a deficient immune system. Full article
(This article belongs to the Special Issue Bioactive Compounds in Food: Analysis and Human Health)
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