Biology Meets Mineralogy: Investigations into Biomolecule Interactions with Aluminosilicate Clay Minerals and Layered Double Hydroxides

A special issue of Minerals (ISSN 2075-163X). This special issue belongs to the section "Clays and Engineered Mineral Materials".

Deadline for manuscript submissions: closed (13 October 2023) | Viewed by 1820

Special Issue Editors


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Guest Editor
USDA-ARS United States Salinity Laboratory, Riverside, CA, USA
Interests: mineral surface processes; soil biogeochemistry

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Guest Editor
Independent Researcher, Dunedin, New Zealand
Interests: origin and early evolution of life; Maillard reaction; RNA

Special Issue Information

Dear Colleagues,

Interactions of biomolecules (e.g., nucleic acids, nucleotides, proteins, peptides, amino acids, polysaccharides, simple sugars, and organic acids) with aluminosilicate clay minerals (e.g., kaolinite, montmorillonite, illite, pyrophyllite, and allophane) and layered double hydroxides (LDHs) (e.g., green rust and hydrotalcite) collectively underlie key processes in soil biogeochemistry, industrial processing, geobiology, biotechnology, nanotechnology, and agriculture. These interactions are thus of great interest to researchers in several fields, including in the study of the origin of life. Many advancements have been made in unraveling the mechanisms behind biomolecule–aluminosilicate clay/LDH interactions that highlight the influence of mineralogy, biomolecule characteristics, and solution conditions on the reaction dynamics. There exist many insights relating to these systems that are currently unrealized and will be the key to future progress in a wide range of disciplines.

We welcome new advancements in the area of biomolecule interactions involving these prominent mineral surfaces. This includes, but is not be limited to, experimental and computational studies of protein adsorption onto clay minerals, mineral-catalyzed nucleic acid transformation, and enhancement of reactions that might have played a role in the origin of life.

Dr. Michael Schmidt
Dr. Harold S. Bernhardt
Guest Editors

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Keywords

  • adsorption 
  • clay
  • nucleic acids 
  • proteins 
  • layered double hydroxides 
  • peptides 
  • sugars 
  • catalysis

Published Papers (1 paper)

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Research

19 pages, 6553 KiB  
Article
Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies
by Hassan Ahmed Rudayni, Malak Aladwani, Lina M. Alneghery, Ahmed A. Allam, Mostafa R. Abukhadra and Stefano Bellucci
Minerals 2023, 13(4), 567; https://doi.org/10.3390/min13040567 - 18 Apr 2023
Cited by 2 | Viewed by 1352
Abstract
The kaolinite sheets were scrolled by sonication-induced chemical delamination processes into well-developed nanotubes (KNs) which were used as substrates for microwave-based ZnO nanoparticles (ZnO/KNs). The biological activities of synthetic ZnO/KNs structures, in terms of the antioxidant and antidiabetic properties, were assessed in comparative [...] Read more.
The kaolinite sheets were scrolled by sonication-induced chemical delamination processes into well-developed nanotubes (KNs) which were used as substrates for microwave-based ZnO nanoparticles (ZnO/KNs). The biological activities of synthetic ZnO/KNs structures, in terms of the antioxidant and antidiabetic properties, were assessed in comparative studies with the separated phases of the synthetic ZnO and KNs as well as the commercially used ZnO. The KNs substrate resulted in a notable enhancement in the antioxidant and antidiabetic properties of ZnO, which was assigned positive influence on the surface area, interactive interfaces, charge separation, and agglomeration properties of ZnO in addition to the detectable bioactive properties of the KNs structure. The ZnO/KNs structure achieved remarkable scavenging efficiencies for 1, 1-diphenyl-2-picrylhydrazil (DPPH) (89.8 ± 1.57%), nitric oxide (90.6 ± 1.63%), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) (86.8 ± 1.28%), and superoxide (43.9 ± 1.72%) radicals. Additionally, it shows high inhibition effects on porcine α-amylase (84.3 ± 1.92%), crude α-amylase (70.6 ± 1.37%), pancreatic α-Glucosidase (94.7 ± 1.54%), crude α-Glucosidase (95.4 ± 1.64%), and amyloglucosidase (95.3 ± 1.32%) enzymes. This antidiabetic activity is significantly higher than the activity of miglitol and close to or slightly higher than acarbose, which leads us to recommend the use of ZnO/KNs when considering the cost and side effects of the commercially used drugs. Full article
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