Special Issue "Mobile Genetic Elements in Pathogens"
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 1207
Interests: characterization of mobile genetic elements carrying resistance genes and their mobility by conjugation and transformation; genomics; microbiome; probiotics and bacteriocins
The microbial mobilome is defined as the complete set of mobile genetic elements (MGEs) present in the microbiome, including plasmids (conjugative and nonconjugative), transposons, integrative and conjugative elements (ICEs, formerly called conjugative transposons), bacteriophages, integrons, insertion sequences (ISs), mobilizable elements, and genomic islands. The acquisition of new genetic material by horizontal gene transfer (HGT) mediated by MGEs significantly drives bacterial genome evolution and is an important source of bacterial diversity, which shapes the structure of microbial communities. MGEs are responsible for the spread of antibiotic resistance and virulence genes in microbial communities by intracellular and intercellular DNA trafficking, which contributes to the adaptability of pathogenic microorganisms in the clinical setting. Metagenomic studies have recently implemented the characterization of MGEs, revealing further insights into the effects of MGEs in shaping the properties of the microbiota; however, functional studies of MGEs are still needed.
This Special Issue will focus on Mobile Genetic Elements and their mobility by horizontal gene transfer linking MGEs and HGT strategies and their complex interactions with the microbial host.
Knowledge in this field will help understanding how MGEs evolve and spread antibiotic resistance and virulence genes. Metagenomic studies will provide new genetic information on the evolutionary impact of MGEs on the microbiome and their functional effects.
We are pleased to invite you to contribute to this Special Issue of Microorganisms by submitting original research articles and review articles related to mobile genetic elements in pathogens.
Prof. Dr. Maria Santagati
Prof. Dr. Francesco Iannelli
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Mobile Genetics Elements
- Integrative Conjugative Elements
- Genomic Islands
- Horizontal Gene Transfer
- Microbial Pathogens