The Macrophages Role in Viral Infections

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 606

Special Issue Editor

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy
Interests: virus evolution; macrophages; HIV pathogenesis; antivirals; HIV chemotherapy; microbicides; viral resistance; neuroAIDS; mechanisms of virus entry; chemokines and chemokine receptors; role of astrocytes and neurons in HIV infection
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Special Issue Information

Dear Colleagues,

Macrophages play a crucial role in the pathogenesis and progression of virus-related infections. Different mechanisms and processes of viruses can establish acute, latent, or persistent infections in macrophages, and have been described and substantiated by in vitro and in vivo evidence. Indeed, macrophage receptors and intracellular pathways, cellular metabolism, and restriction factors, are involved in controlling the virus life cycle and tuning the cellular response to infection. Moreover, despite enhancing inflammation progression, infected macrophages generally display abolished apoptosis and restricted cytopathic effect, which sustains the virus’ production. At the same time, characterization of the macrophages mechanisms that interfere with viral replication and regulate the inflammatory cascade as well as identifying novel cellular targets for developing antivirals drugs and antiviral therapy approaches is a new challenge. All researchers working in the fields of human viral infections and macrophages are cordially invited to contribute original research papers or reviews to this Special Issue of Microorganisms.

Prof. Dr. Stefano Aquaro
Guest Editor

Manuscript Submission Information

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  • macrophages
  • monocytes
  • reservoir
  • virus receptors
  • viruses
  • virus pathogenesis
  • apoptosis
  • virus genome
  • virus evolution
  • virus entry
  • virus replication
  • viral enzymes
  • antivirals
  • drug design
  • antiviral activity
  • antiviral therapy
  • antiviral resistance

Published Papers

There is no accepted submissions to this special issue at this moment.
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