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Special Issue "Gut Microbiota and the Impact on Animal Models of Disease"
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 13349
Special Issue Editor
Interests: gut microbiota; colon cancer; animal model; genetics; epigenetics; metagenomics
Special Issue Information
During the past decade, it has become increasing clear that the commensal gut microbiota performs a delicate balancing act with its host, playing a nearly indispensable role in nutritional metabolism on the one hand, and creating a community that increases one’s risk to developing disease. While many pathogenic bacteria with clear toxic pathways have been identified, the role of commensal microbes in disease susceptibility is not understood as well. Recent studies in animal models of intestinal cancer in an otherwise specific pathogen-free environment have shown differential susceptibility to disease associated with different complex gut microbiota. There are many putative genera that associate with either increased or decreased risk. It is becoming clearer that single microbes may not be a specific cause, but rather complex combinations and interactions altering the metabolic profile are likely driving this susceptibility.
The aim of this Special Issue is to begin to resolve the role of microbes in disease development, especially in animal models of disease, and relating that to the larger translational implication to human disease. This can involve many biological systems, including infection and immunity, metabolism, genetic, and epigenetic influences.
We are pleased and excited to invite you to submit to this Special Issue that will address our current understanding of the gut microbiota effects on animal models of disease, with an emphasis on intestinal cancer and metabolic disease models, and strategies to resolve the multiple roles of the animal-associated microbiota.
In this Special Issue, we are welcoming original research articles and reviews. Research areas may include (but are not limited to) the following: gut, skin, vaginal, or other specific microbiota and the biological role in animal models. While the focus will be vertebrate mammals, other species including zebrafish and invertebrate model systems are welcome.
I look forward to receiving your contributions.
Dr. James Amos-Landgraf
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.