Dear Colleagues,

Antimicrobial resistance is a major threat challenging human advancement in this century, and has emerged as a global issue negatively affecting health, food security, and development. Historically, the discovery of different classes of antibiotics had a tremendous impact on the treatment, control, and prevention of diseases in humans and animals. While the use of antibiotics in food animals has improved intestinal health, reduced disease, and alleviated reproductive problems, the emergence of drug-resistant pathogens and their potential transmission to humans have restricted their applications in production. In recent years, several drug-resistant pathogens have been implicated as etiological agents of human disease, including those contributing significantly to the burden of foodborne disease. Consequentially, significant changes and adjustments in production practices have been introduced in an otherwise organized production setting where antibiotics were successfully relied upon to obtain optimal production. In response to the mounting evidence connecting antibiotic use in food animals and human health risks, the establishment of strict requirements for the distribution and use of clinically relevant antibiotics, and animal feeds or water containing such drugs, have resulted. Given the emergence of multidrug-resistant strains of pathogens in the food chain, there has been a growing interest in identifying solutions addressing such concerns. Preventing and limiting the spread of multidrug-resistant infections and discovering and evaluating alternatives to antibiotics and similar mitigation approaches are potential ways to handle this problem. The development of improved diagnostic tests, understanding transmission mechanisms, and introducing targeted education and outreach programs could help. This Special Issue will be a collection of research articles, reviews, and short communications of advances in scientific research and programs in the areas mentioned above intended to address problems associated with antibiotic resistance development.

Prof. Dr. Anup Kollanoor Johny
Guest Editor

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• antimicrobial resistance
• food animals
• agriculture
• poultry
• alternatives
• diagnostic tools
• mechanisms of transmission
• education
• outreach
• food animal/poultry–human interface
• environment
• resistome
• microbiome
• metabolome
• stewardship
• mitigation
• wildlife