Special Issue "Clostridium difficile"
Deadline for manuscript submissions: closed (1 May 2020) | Viewed by 30080
Interests: microbial ecology; microbiota-host cross-talk; health
Special Issues, Collections and Topics in MDPI journals
Special Issue in Microorganisms: Gut Microbiome of Farm Animals in Health and Disease 2.0
Clostridium (syn. Clostridioides) difficile inhabits the gut of humans and animals. The sporulation/germination life cycle allows this bacterium to survive in harsh environments and colonise host niches when conditions are favourable. Virulent ribotypes of C. difficile are common pathogens and are involved in serious gastrointestinal infections. C. difficile has emerged as an important pathogen in clinical settings and is a severe threat in veterinary medicine, where it often spontaneously causes diseases of unknown aetiology in farm animals. The zoonotic potential of C. difficile and resistant pathogens is of major importance for human and animal health. There are still fundamental knowledge gaps that have spurred an urgent need to explore C. difficile's biology and factors that contribute to the transmission and development of infection.
This Special Issue, entitled "Clostridium difficile", aims to present recent research on various aspects of C. difficile, including ecology, virulence, and infection course under in vivo and in vitro conditions. Some of its central topics include but are not limited to C. difficile colonization, interaction with the gut microbiota and the host, immune response, strategies to reduce C. difficile infections in humans and animals, and problems of antibiotic resistance and zoonosis.
Research articles, review articles, and short communications are welcome. We look forward to publishing your work.
Dr. Łukasz M. Grześkowiak
Manuscript Submission Information
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- Clostridium difficile
- Clostridioides difficile
- gut microbiota