Development of Nanotechnology-Directed Drug and Gene Delivery Carriers against Infectious Diseases

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 150

Special Issue Editors

Department of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL 32608, USA
Interests: nanotechnology; immunotherapy; brain tumor
Special Issues, Collections and Topics in MDPI journals
Department of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL 32608, USA
Interests: biomarkers; resistance; imaging; nanotechnology; long-acting therapeutics; diagnosis; liposomes; lipid nanoparticles
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The emergence of antimicrobial resistance to the existing therapies represents a major challenge towards treatment success against infectious pathogens. Overcoming resistance to the existing therapies requires a combination of drugs with different mechanisms of actions or employing newer modalities such as siRNA/CRISPR Cas9 systems both individually and in combination with a biologic or small molecule encapsulated in a nano carrier for efficient cargo delivery, reducing the therapeutic dose and off-target toxicities. Gene modalities such as mRNA, siRNA, and CRISPR are efficient drug substances that can be directed towards target cellular and tissue compartments for enhanced biodistribution profiles using nanotechnology carriers such as lipid or polymeric nanoparticles, lipopolyplex carriers, and hydrogels.

These goals will only be achieved by joining efforts from multiple disciplines including virology, geneticists, formulation scientists, clinicians, immunologists, medicinal chemists, etc.

The aim of this Special Issue is to provide an adequate multidisciplinary platform for the interchange of valuable information (both basic and applied research) that aids the development of nanoparticulate vaccines against infectious diseases, RNA/CRISPR delivery, and biologics and/ small molecule inhibitors targeted towards reversing antimicrobial resistance to the existing therapies.

As a Guest Editor of the Special Issue, I invite you to submit research articles, review articles, and short communications related to gene and or CRISPR delivery, lipid and polymeric nanoparticulate vaccines and systems loading biologics/small molecule inhibitors targeted towards reversing microbial resistance to the existing therapies.

Dr. Héctor R. Méndez-Gómez
Dr. Dhruvkumar M. Soni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • resistance
  • nanotechnology
  • gene delivery
  • vaccines
  • infectious
  • anti-microbial
  • lipid nanoparticles
  • biologics
  • small molecule inhibitors
  • polymeric nanoparticles
  • CRISPR
  • elimination

Published Papers

There is no accepted submissions to this special issue at this moment.
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