Anaerobic Bacteria and Their Resistance Mechanisms

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 456

Special Issue Information

Dear Colleagues,

Strict anaerobic bacteria are important constitutents of the normal human microbiota and they have been implicated in a wide range of infectious processes, that may be serious or life-threatening. The isolation and correct identification of these bacteria may still be challenging in many settings worldwide, due to their laborious culture, extensive laboratory requirements (suitable anaerobiosis) and the fastidious nature of these microorganisms. Susceptibility testing for anerobic bacteria is seldom performed (mainly by national reference laboratories) and there is limited information available on their resistance trends, compared to other bacterial genera; susceptibility testing for anaerobic bacteria is also hindered by the lack of uniform standard operating procedures, while reliable testing methods (i.e., agar diffusion) are expensive and labor-intensive. For many years, the treatment choice in these infections has been mostly empirical, as resistance levels in anaerobes were previously thought to be predictable. Antibiotic resistance in anaerobes remains a neglected field of study; nevertheless, in recent decades, there has been an increasing number of reports on the emergence and molecular mechanisms of beta-lactam and metronidazole resistance in anaerobic bacteria, especially among the members of the Bacteroides/Parabacteroides genus. As these antibiotics are considered the backbone of the treatment of anaerobic infections, increasing levels of resistance may hold significant therapeutic implications for clinicians.

The purpose of this Special Issue is to enrich the existing literature regarding the emergence, testing methods, and mechanisms of antibiotic resistance in strict anaerobic bacteria, therefore the submission of original articles, and review papers on these topics are welcome.

Prof. Dr. Edit Urbán
Dr. Márió Gajdács
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • anaerobes
  • resistance mechanisms
  • antibiotic susceptibility
  • testing PCR and sequencing
  • cfiA/cfxA genes
  • beta-lactam antibiotics
  • nim genes
  • metronidazole
  • microbiome clinical medicine

Related Special Issue

Published Papers

There is no accepted submissions to this special issue at this moment.
Back to TopTop