Infection Diseases and Chronic Health Conditions
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 789
Interests: pediatrics;clinical genetics;inherited metabolic disorders;newborn screening;phenylketonuria
Special Issues, Collections and Topics in MDPI journals
Chronic conditions represent a broad spectrum of chronic and complex health conditions, both communicable and non-communicable. Although it is common to approach chronic and infectious diseases as having completely distinct aetiologies and approach, there is an increasing acknowledgement for a closer relationship between them. In this context, COVID-19 has emphasized even more the existence of common determinants that underlie both.
Rather than discussing the role of infections as major determinants of chronic diseases, this Special Issue aims at focusing on the complex and bidirectional relationship between these two apparently distinguished groups of disorders.
There are several reasons why an infection may be associated with a chronic condition: the infection may be more prevalent in patients with the chronic disease (for a compromised immune response); the pathogen increases the risk of getting the disease, or causes the disease only when combined with other causal factors (genetic factors, or toxic exposure). Infection (such as seasonal influenza) may occur in the background of an established chronic disease and interact with it, modifying its natural history (increasing the risk of hospital admissions and death). Pathogens can also cause an “immunologic scarring” even after resolution, accounting for a wide range of chronic effects.
More studies on interactions between infections and chronic diseases might help to understand and optimize the management of both and would help to apply pharmacologic approaches that are able to manage chronic diseases while treating infections.
Dr. Albina Tummolo
Manuscript Submission Information
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- chronic conditions
- genetic diseases
- immune system