Dear Colleagues,

SARS-CoV-2 infected more than 6 million people worldwide, with different clinical outcomes. Continuous new challenges are emerging for the rapid mutations in the viral genome. Scientists are working hard to search for appropriate advanced therapies to treat COVID-19 and investigate new safe and effective vaccines capable of efficiently prevent the infection.

Until now, different vaccines have been licensed sooner and others are under investigation. Although the vaccination strongly reduced severe illness, and new findings and research continuously expand our knowledge about COVID-19 and SARS-CoV-2 infection, it is critical to investigate the type and the timing of immune response generated using licensed and/or new experimental vaccines, and new efficient approaches based on different delivery systems or route of vaccination.

The Special Issue “Immune Modulation to SARS-CoV-2 Vaccination and Infection” aims to assemble a collection of original research articles and reviews that explore, in pre-clinical and clinical studies, the innate and adaptive immune response elicited by infection with SARS-CoV-2, or induced by different type of vaccines against SARS-CoV-2. Research works evaluating the modulation of the immune response to vaccination and/or infection, studying the type, the magnitude, the quality, and the persistence of the immune response, are welcomed.

Dr. Fabio Fiorino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• COVID-19
• SARS-CoV-2
• infection
• immune response
• antibody response
• memory cells
• vaccine
• vaccine delivery
• route of immunization
• immune persistence