Special Issue "Enterotoxigenic Escherichia coli Infection and Vaccine-Mediated Immunity"
Deadline for manuscript submissions: 30 December 2023 | Viewed by 2507
Interests: enteric bacterial and viral vaccines; COVID-19 vaccines; molecular mediators of microbial adherence
Interests: ETEC epidemiology; immunology; vaccines
Interests: enterotoxigenic E. coli (ETEC); vaccines; pathogen–host interactions
2. Lead, Institute for Developing Science and Health Initiatives (ideSHi), Dhaka, Bangladesh
Interests: immunology and molecular genomics of enteric and respiratory infections, including COVID-19 infections in LMICs; vaccine evaluation in endemic settings
Enterotoxigenic Escherichia coli (ETEC) is the most prevalent bacterial pathogen causing acute watery diarrhea in young children in low- and middle-income Countries (LMICs). The high ETEC burden results in children facing numerous diarrhea episodes, which potentially contributes to poor growth and cogntivie development. ETEC also remains the leading cause of diarrhea in travelers and military visiting endemic areas. The WHO recently re-affirmed ETEC as a vaccine priority and, given its recogncition as a signficant AMR threat, public health stakeholders have urged that the development for a vaccine be accelerated.
The aim of this Special Issue of Microorganisms is to present articles that provide an in-depth look at the current state of ETEC vaccines and the supportive information necessary to advance these vaccines to licensure. Topics:
- Assessment of the value of vaccines;
- Epidemiology and global burden;
- Host parameters and genomics that predict responses;
- Application of new omics technologies for the characterization of host responses;
- Preclinical evaluation of vaccine candidates and models of disease;
- Vaccine candidates in clinical trials and in human challenge models.
It is expected that this Special Issue of Microorganisms will accelerate the field toward an ETEC vaccine(s) licensure so the negative impact of this insidious disease can be minimized as soon as possible.
Dr. Frederick J. Cassels
Dr. August Louis Bourgeois
Prof. Dr. James M. Fleckenstein
Dr. Firdausi Qadri
Dr. Richard I. Walker
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- enterotoxigenic Eschericia coli
- colonization factors
- non-canonical antigens
- ETEC genomics and proteomics
- ETEC vaccines
- ETEC human challenge model
- ETEC animal models
- preclinical evaluation ETEC vaccines
- host parameters ETEC vaccines
- mucosal and systemic ETEC immunity