Antimicrobial Properties of Plants-Derived Natural Products
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 4559
Special Issue Editor
2. TOXRUN—Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal
Interests: evidence-based medicine; phytochemistry; phytopharmacology; drug discovery; bioactive molecules; functional foods; nutraceuticals; oxidative stress; inflammation; infectious diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Medicinal plants have long been recognized for their multiple potentialities. Across a broad range of bioactive compounds, a multitude of studies have been performed, from basic to increasingly complex ones, to deepen knowledge on the pharmacological potential of both plants extracts and their isolated constituents. Among the main concerns in terms of health, infectious diseases have proved to be a significant challenge, motivated by the increasing rates of acquired resistance to currently available drugs, but also by their adverse effects and associated toxicity, which have been exacerbated due to the increasing use of higher doses, and even their combination. As a result of this current scenario, more and more studies have focused on discovering the therapeutic potential of plants and deepening their mechanism of action, with a view to providing new drugs, more effective and safer than those currently available. From a biochemical point of view, among the various compounds present and currently identified and chemically characterized, several still remain unknown, while to those already discovered, the screening studies were performed to address their biological activity have been promising, although to some phytochemicals metabolization needs to take place so that they become available and biologically active, the direct applicability of such findings in in vivo experiments being questionable. Lastly, and with a view of translating in vivo findings to clinical scenarios, intensive translational research has been conducted to date, not only to validate the main findings obtained by in vitro experiments, but also to project the upcoming use of such promising molecules with outstanding antimicrobial activity for further chemical synthesis and assessment of their pharmacological activity in clinical trials. Taking this in mind, the current Special Issue encourages the submission of in vitro, in vivo, and clinical studies addressing the antimicrobial effects and molecular mechanisms of plant-derived bioactive compounds, including chemical characterization and quantification, determination of mechanisms of action, target identification, structure–activity relationships, and therapeutic applications. Original articles, review articles, critical reviews, mini-reviews, comments, perspectives, and even short communications are particularly welcome. We look forward to receiving your contributions and welcome you to join us in this effort.
Prof. Dr. Natália Cruz-Martins
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Infectious diseases
- inflammation
- bioactive molecules
- phytochemistry
- drug discovery
- antimicrobials
