Recent Advance in Medical and Rehabilitation Robots

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 18067

Special Issue Editors


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Guest Editor
Beijing Key Laboratory of Advanced Manufacturing Technology, Beijing University of Technology, Beijing 100021, China
Interests: upper limb rehabilitation; assistive wearable robot; human–robot interaction; muscular fatigue; telescopic robot
School of Electromechanical Engineering, Beijing Information Science and Technology University, Beijing 100192, China
Interests: rehabilitation robot; medical and surgical robots; biomechanics

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Guest Editor
Dean, Future Integration College, Jeonju University, 303 Cheonjam-ro, Wansan-gu, Jeonju-si, Jeollabuk-do, Republic of Korea
Interests: machine vision; artificial intelligence; human–robot interaction

Special Issue Information

Dear Colleagues,

By incorporating the advantages of miniaturization and the efficiency of related technology components, medical and rehabilitation robots as complex human–machine systems have been used in numerous clinical applications, such as in external fixation, as surgical robots, in upper/lower limb rehabilitation, as wearable robots, etc., for reducing physical trauma, improving surgical operation efficiency, and increasing the strength and precision capabilities of the human body. In the past 10 years, a series of intelligent actuators/sensors, control strategies, and new structures/configurations have been successively developed, greatly and significantly facilitating the progress of medical and rehabilitation robots. With the development of artificial intelligence technology, in particular, operating performance and surgical efficiency have been greatly improved. In order to further advance medical and rehabilitation technologies and their applications in clinical areas, this Special Issue seeks to showcase research papers, communications, and review articles focusing on recent advances in medical and rehabilitation robots, including with regard to their design, modeling, simulation, experiments, and applications.

We look forward to receiving your submissions!

Dr. Leiyu Zhang
Dr. Peng Su
Prof. Dr. Dongsoong Han
Guest Editors

Manuscript Submission Information

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Keywords

  • medical robot
  • rehabilitation robot
  • control strategy
  • human–machine interaction
  • performance evaluation

Published Papers (12 papers)

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Research

11 pages, 2420 KiB  
Article
A Mechanical Evaluation of a Robot-Assisted Cutting Cornea Based on Force Response
by Qinran Zhang, Jingyu Zhao, Sikai Wang, Shijing Deng and Peng Su
Micromachines 2023, 14(8), 1634; https://doi.org/10.3390/mi14081634 - 19 Aug 2023
Cited by 1 | Viewed by 814
Abstract
The aim of this paper is to propose laws of trephine operation based on a robot-assisted cutting cornea in order to obtain better microsurgical effects for keratoplasty. Using a trephine robot integrated with a microforce sensor and a handheld trephine manipulator, robotic and [...] Read more.
The aim of this paper is to propose laws of trephine operation based on a robot-assisted cutting cornea in order to obtain better microsurgical effects for keratoplasty. Using a trephine robot integrated with a microforce sensor and a handheld trephine manipulator, robotic and manual experiments were performed, with porcine corneas as the test subjects. The effect of trephine operational parameters on the results reflected by the biomechanical response is discussed, and the parameters include linear velocity, rotating angle, and angular velocity. Using probability density functions, the distributions of the manual operational parameters show some randomness, and there is a large fluctuation in the trephine force during the experiments. The biomechanical response shows regular trends in the robotic experiments even under different parameters, and compared to manual trephination, the robot may perform the operation of trephine cornea cutting more stably. Under different operational parameters, the cutting force shows different trends, and the optimal initial parameters that result in better trephine effects can be obtained based on the trends. Based on this derived law, the operational parameters can be set in robotic trephination, and surgeons can also be specially trained to achieve a better microsurgical result. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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14 pages, 1749 KiB  
Article
Hemisphere Tabulation Method: An Ingenious Approach for Pose Evaluation of Instruments Using the Electromagnetic-Based Stereo Imaging Method
by Zhongjie Long, Yongting Chi, Dejin Yang, Zhouxiang Jiang and Long Bai
Micromachines 2023, 14(2), 446; https://doi.org/10.3390/mi14020446 - 14 Feb 2023
Cited by 1 | Viewed by 1285
Abstract
Drilling of a bone surface often occurs in clinical orthopaedic surgery. The position and orientation of the instrument are the most important factors in this process. Theoretically, some mechanical components may assist in orienting an instrument to certain bone shapes, such as the [...] Read more.
Drilling of a bone surface often occurs in clinical orthopaedic surgery. The position and orientation of the instrument are the most important factors in this process. Theoretically, some mechanical components may assist in orienting an instrument to certain bone shapes, such as the knee joint and caput femoris. However, the mechanical assisting component does not seem to work in some confined spaces where the bone shape is a free-form surface. In this paper, we propose an ingenious hemisphere tabulation method (HTM) for assessing the pose accuracy of an instrument. The acquisition and assessment of HTM is conducted based on an electromagnetic-based stereo imaging method using a custom-made optical measurement unit, and the operation steps of HTM are described in detail. Experimental results based on 50 tests show that the HTM can identify ideal poses and the evaluated pose of an instrument location on a hemisphere model. The mean error of pose localisation is 7.24 deg, with a range of 1.35 to 15.84 and a standard of 3.66 deg, which is more accurate than our previous method. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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20 pages, 8992 KiB  
Article
Design and Experiment of an Ultrasound-Assisted Corneal Trephination System
by Jingjing Xiao, Jialong Chen, Mengqiong Li and Leiyu Zhang
Micromachines 2023, 14(2), 438; https://doi.org/10.3390/mi14020438 - 12 Feb 2023
Viewed by 1213
Abstract
According to the advantages of ultrasonic vibration cutting, an ultrasound-assisted corneal trepanation robotic system is developed to improve the accuracy of corneal trephination depth and corneal incision quality in corneal trephination operations. Firstly, we analyzed the reasons for the difficulty in controlling the [...] Read more.
According to the advantages of ultrasonic vibration cutting, an ultrasound-assisted corneal trepanation robotic system is developed to improve the accuracy of corneal trephination depth and corneal incision quality in corneal trephination operations. Firstly, we analyzed the reasons for the difficulty in controlling the depth of trephination in corneal transplantations from the perspective of the biomechanical properties of the cornea. Based on the advantages of ultrasonic vibration cutting, we introduced an ultrasonic-vibration-assisted cutting method for corneal trephination and analyzed the cutting mechanism. Secondly, we described the surgical demands of corneal trephination and listed the design requirements of a robotic system. Thirdly, we introduced the design details of said system, including the system’s overall structure, the ultrasound-assisted end effector, the key mechanisms of the robotic system, and the human–machine interaction interface. We designed the end effector based on ultrasonic vibration cutting and its eccentric adjustment system in an innovative way. Additionally, we then presented a procedure for robot-assisted corneal trephination. Finally, we performed several cutting experiments on grapes and porcine eyeballs in vitro. The results show that, compared with manual trephine, ultrasound-assisted corneal trephination has a better operation effect on the accuracy of corneal trephination depth and corneal incision quality. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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17 pages, 4861 KiB  
Article
Dynamic and Functional Alterations of Neuronal Networks In Vitro upon Physical Damage: A Proof of Concept
by Sàlem Ayasreh, Imanol Jurado, Clara F. López-León, Marc Montalà-Flaquer and Jordi Soriano
Micromachines 2022, 13(12), 2259; https://doi.org/10.3390/mi13122259 - 19 Dec 2022
Cited by 2 | Viewed by 1362
Abstract
There is a growing technological interest in combining biological neuronal networks with electronic ones, specifically for biological computation, human–machine interfacing and robotic implants. A major challenge for the development of these technologies is the resilience of the biological networks to physical damage, for [...] Read more.
There is a growing technological interest in combining biological neuronal networks with electronic ones, specifically for biological computation, human–machine interfacing and robotic implants. A major challenge for the development of these technologies is the resilience of the biological networks to physical damage, for instance, when used in harsh environments. To tackle this question, here, we investigated the dynamic and functional alterations of rodent cortical networks grown in vitro that were physically damaged, either by sequentially removing groups of neurons that were central for information flow or by applying an incision that cut the network in half. In both cases, we observed a remarkable capacity of the neuronal cultures to cope with damage, maintaining their activity and even reestablishing lost communication pathways. We also observed—particularly for the cultures cut in half—that a reservoir of healthy neurons surrounding the damaged region could boost resilience by providing stimulation and a communication bridge across disconnected areas. Our results show the remarkable capacity of neuronal cultures to sustain and recover from damage, and may be inspirational for the development of future hybrid biological–electronic systems. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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18 pages, 8330 KiB  
Article
Design and Load Kinematics Analysis of Rollover Rehabilitation Mechanism Fitting Human Motion Curve
by Peng Su, Yuelin Zhang, Qinglong Lun, Chao Ma, Yi Liu, Leiyu Zhang and Long Huang
Micromachines 2022, 13(12), 2064; https://doi.org/10.3390/mi13122064 - 25 Nov 2022
Cited by 1 | Viewed by 1167
Abstract
Supine rollover plays an important role in the prevention of pressure sores in long-term bedridden patients. It is of great significance to study the mechanism of human supine rollover movement and to design the rehabilitation rollover mechanism in line with man-machine cooperation. In [...] Read more.
Supine rollover plays an important role in the prevention of pressure sores in long-term bedridden patients. It is of great significance to study the mechanism of human supine rollover movement and to design the rehabilitation rollover mechanism in line with man-machine cooperation. In human supine rollover movement, shoulder and hip are the key parts of force application. Based on anatomical theory, the motion trajectory information of shoulder and hip skeletal rehabilitation parts is collected by combining optical motion capture and rigid body modeling. Following a kinematics simulation analysis, the simulation curve was compared with the experimental curve track; the numerical difference was small. It is proved that the simulation model is correct, and it is also shown that the designed rehabilitation rollover mechanism can better reproduce the natural rolling motion state of the human body. It can meet the requirements of human-machine synergistic assisted lateral roll rehabilitation aids and provides a solution for pressure sore prevention. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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33 pages, 6416 KiB  
Article
Impedance Iterative Learning Backstepping Control for Output-Constrained Multisection Continuum Arms Based on PMA
by Yuexuan Xu, Xin Guo, Jian Li, Xingyu Huo, Hao Sun, Gaowei Zhang, Qianqian Xing, Minghe Liu, Tianyi Ma and Qingsong Ding
Micromachines 2022, 13(9), 1532; https://doi.org/10.3390/mi13091532 - 16 Sep 2022
Cited by 5 | Viewed by 1440
Abstract
Background: Pneumatic muscle actuator (PMA) actuated multisection continuum arms are widely applied in various fields with high flexibility and bionic properties. Nonetheless, their kinematic modeling and control strategy proves to be extremely challenging tasks. Methods: The relationship expression between the deformation parameters and [...] Read more.
Background: Pneumatic muscle actuator (PMA) actuated multisection continuum arms are widely applied in various fields with high flexibility and bionic properties. Nonetheless, their kinematic modeling and control strategy proves to be extremely challenging tasks. Methods: The relationship expression between the deformation parameters and the length of PMA with the geometric method is obtained under the assumption of piecewise constant curvature. Then, the kinematic model is established based on the improved D-H method. Considering the limitation of PMA telescopic length, an impedance iterative learning backstepping control strategy is investigated. For one thing, the impedance control is utilized to ensure that the ideal static balance force is maintained constant in the Cartesian space. For another, the iterative learning backstepping control is applied to guarantee that the desired trajectory of each PMA can be accurately tracked with the output-constrained requirement. Moreover, iterative learning control (ILC) is implemented to dynamically estimate the unknown model parameters and the precondition of zero initial error in ILC is released by the trajectory reconstruction. To further ensure the constraint requirement of the PMA tracking error, a log-type barrier Lyapunov function is employed in the backstepping control, whose convergence is demonstrated by the composite energy function. Results: The tracking error of PMA converges to 0.004 m and does not exceed the time-varying constraint function through cosimulation. Conclusion: From the cosimulation results, the superiority and validity of the proposed theory are verified. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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28 pages, 13435 KiB  
Article
Interval Type-3 Fuzzy Adaptation of the Bee Colony Optimization Algorithm for Optimal Fuzzy Control of an Autonomous Mobile Robot
by Leticia Amador-Angulo, Oscar Castillo, Patricia Melin and Juan R. Castro
Micromachines 2022, 13(9), 1490; https://doi.org/10.3390/mi13091490 - 07 Sep 2022
Cited by 14 | Viewed by 1736
Abstract
In this study, the first goal is achieving a hybrid approach composed by an Interval Type-3 Fuzzy Logic System (IT3FLS) for the dynamic adaptation of α and β parameters of Bee Colony Optimization (BCO) algorithm. The second goal is, based on BCO, [...] Read more.
In this study, the first goal is achieving a hybrid approach composed by an Interval Type-3 Fuzzy Logic System (IT3FLS) for the dynamic adaptation of α and β parameters of Bee Colony Optimization (BCO) algorithm. The second goal is, based on BCO, to find the best partition of the membership functions (MFs) of a Fuzzy Controller (FC) for trajectory tracking in an Autonomous Mobile Robot (AMR). A comparative with different types of Fuzzy Systems, such as Fuzzy BCO with Type-1 Fuzzy Logic System (FBCO-T1FLS), Fuzzy BCO with Interval Type-2 Fuzzy Logic System (FBCO-IT2FLS) and Fuzzy BCO with Generalized Type-2 Fuzzy Logic System (FBCO-GT2FLS) is analyzed. A disturbance is added to verify if the FBCO-IT3FLS performance is better when the uncertainty is present. Several performance indices are used; RMSE, MSE and some metrics of control such as, ITAE, IAE, ISE and ITSE to measure the controller’s performance. The experiments show excellent results using FBCO-IT3FLS and are better than FBCO-GT2FLS, FBCO-IT2FLS and FBCO-T1FLS in the adaptation of α and β parameters. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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14 pages, 1231 KiB  
Article
Deep Convolutional Neural Network for EEG-Based Motor Decoding
by Jing Zhang, Dong Liu, Weihai Chen, Zhongcai Pei and Jianhua Wang
Micromachines 2022, 13(9), 1485; https://doi.org/10.3390/mi13091485 - 07 Sep 2022
Cited by 3 | Viewed by 1883
Abstract
Brain–machine interfaces (BMIs) have been applied as a pattern recognition system for neuromodulation and neurorehabilitation. Decoding brain signals (e.g., EEG) with high accuracy is a prerequisite to building a reliable and practical BMI. This study presents a deep convolutional neural network (CNN) for [...] Read more.
Brain–machine interfaces (BMIs) have been applied as a pattern recognition system for neuromodulation and neurorehabilitation. Decoding brain signals (e.g., EEG) with high accuracy is a prerequisite to building a reliable and practical BMI. This study presents a deep convolutional neural network (CNN) for EEG-based motor decoding. Both upper-limb and lower-limb motor imagery were detected from this end-to-end learning with four datasets. An average classification accuracy of 93.36 ± 1.68% was yielded on the four datasets. We compared the proposed approach with two other models, i.e., multilayer perceptron and the state-of-the-art framework with common spatial patterns and support vector machine. We observed that the performance of the CNN-based framework was significantly better than the other two models. Feature visualization was further conducted to evaluate the discriminative channels employed for the decoding. We showed the feasibility of the proposed architecture to decode motor imagery from raw EEG data without manually designed features. With the advances in the fields of computer vision and speech recognition, deep learning can not only boost the EEG decoding performance but also help us gain more insight from the data, which may further broaden the knowledge of neuroscience for brain mapping. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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18 pages, 7785 KiB  
Article
Study on the Modeling and Compensation Method of Pose Error Analysis for the Fracture Reduction Robot
by Minghe Liu, Jian Li, Hao Sun, Xin Guo, Bokai Xuan, Lifang Ma, Yuexuan Xu, Tianyi Ma, Qingsong Ding and Baichuan An
Micromachines 2022, 13(8), 1186; https://doi.org/10.3390/mi13081186 - 27 Jul 2022
Cited by 5 | Viewed by 1331
Abstract
Background: In the process of fracture reduction, there are some errors between the actual trajectory and the ideal trajectory due to mechanism errors, which would affect the smooth operation of fracture reduction. To this end, based on self-developed parallel mechanism fracture reduction robot [...] Read more.
Background: In the process of fracture reduction, there are some errors between the actual trajectory and the ideal trajectory due to mechanism errors, which would affect the smooth operation of fracture reduction. To this end, based on self-developed parallel mechanism fracture reduction robot (FRR), a novel method to reduce the pose errors of FRR is proposed. Methods: Firstly, this paper analyzed the pose errors, and built the model of the robot pose errors. Secondly, mechanism errors of FRR were converted into drive bar parameter’s errors, and the influence of each drive bar parameter on the robot pose error were analyzed. Thirdly, combining with Cauchy opposition-based learning and differential evolution algorithm (DE), an improved whale optimization algorithm (CRLWOA-DE) is proposed to compensate the end-effector’s pose errors, which could improve the speed and accuracy of fracture reduction, respectively. Results: The iterative accuracy of CRLWOA-DE is improved by 50.74%, and the optimization speed is improved by 22.62% compared with the whale optimization algorithm (WOA). Meanwhile, compared with particle swarm optimization (PSO) and ant colony optimization (ACO), CRLWOA-DE is proved to be more accurate. Furthermore, SimMechanics in the software of MATLAB was used to reconstruct the fracture reduction robot, and it was verified that the actual motion trajectory of the CRLWOA-DE optimized kinematic stage showed a significant reduction in error in both the x-axis and z-axis directions compared to the desired motion trajectory. Conclusions: This study revealed that the error compensation in FRR reset process had been realized, and the CRLWOA-DE method could be used for reducing the pose error of the fracture reduction robot, which has some significance for the bone fracture and deformity correction. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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20 pages, 8380 KiB  
Article
Cooperativity Model for Improving the Walking-Assistance Efficiency of the Exoskeleton
by Jianfeng Ma, Decheng Sun, Yongqing Ding, Daihe Luo and Xiao Chen
Micromachines 2022, 13(7), 1154; https://doi.org/10.3390/mi13071154 - 21 Jul 2022
Cited by 1 | Viewed by 1282
Abstract
(1) Background: To enhance the walking-assistance efficiencies of exoskeletons, this paper proposed the biomechanical-based cooperativity model based on a passive exoskeleton prototype to fill the technical gap in exoskeleton design regarding the torque transmission law between humans and exoskeletons. (2) Methods: The cooperativity [...] Read more.
(1) Background: To enhance the walking-assistance efficiencies of exoskeletons, this paper proposed the biomechanical-based cooperativity model based on a passive exoskeleton prototype to fill the technical gap in exoskeleton design regarding the torque transmission law between humans and exoskeletons. (2) Methods: The cooperativity model was used to solve the key system parameters based on the minimum average dispersion degree, in which the average dispersion degree algorithm based on the joint angle was designed and applied. (3) Results: The influence of the cooperativity model on the exoskeleton was indicated by comparing the walking-assistance efficiencies of the exoskeletons with the same structure but with different elastic parameters of the energy storage components, in which the exoskeleton based on the cooperativity design exhibited the highest walking-assistance performance. The walking-assistance efficiency of the exoskeleton with the optimal parameter combinations was also tested by comparing the respiratory metabolisms with and without the exoskeleton, in which the exoskeleton provided the average walking-assistance efficiency of 14.45% for more than 80% of the subjects. (4) Conclusions: The effects of the cooperativity model on exoskeletons were proven, but the accuracy and efficiency of the model still have room for improvement, especially the accuracy of the offset principle. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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24 pages, 11164 KiB  
Article
Equilibrium Conformation of a Novel Cable-Driven Snake-Arm Robot under External Loads
by Long Huang, Bei Liu, Leiyu Zhang and Lairong Yin
Micromachines 2022, 13(7), 1149; https://doi.org/10.3390/mi13071149 - 20 Jul 2022
Cited by 2 | Viewed by 1907
Abstract
Based on the anti-parallelogram mechanism, an approximate cylindrical rolling joint is proposed to develop a novel cable-driven snake-arm robot with multiple degrees of freedom (DOF). Furthermore, the kinematics of the cable-driven snake-arm robot are established, and the mapping between actuator space and joint [...] Read more.
Based on the anti-parallelogram mechanism, an approximate cylindrical rolling joint is proposed to develop a novel cable-driven snake-arm robot with multiple degrees of freedom (DOF). Furthermore, the kinematics of the cable-driven snake-arm robot are established, and the mapping between actuator space and joint space is simplified by bending decoupling motion in the multiple segments. The workspace and bending configurations of the robot are obtained. The static model is established by the principle of minimum potential energy. Furthermore, the simplified cable constraints in the static model are proposed through Taylor expansion, which facilitates the equilibrium conformation analysis of the robot under different external forces. The cable-driven snake-arm robot prototype is developed to verify the feasibility of the robot design and the availability of the static model through the experiments of the free bending motion and the external load on the robot. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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18 pages, 4147 KiB  
Article
Ergonomics Design and Assistance Strategy of A-Suit
by Leiyu Zhang, Xiang Gao, Ying Cui, Jianfeng Li, Ruidong Ge, Zhenxing Jiao and Feiran Zhang
Micromachines 2022, 13(7), 1114; https://doi.org/10.3390/mi13071114 - 15 Jul 2022
Viewed by 1398
Abstract
Concerning the biomechanics and energy consumption of the lower limbs, a soft exoskeleton for the powered plantar flexion of the ankle, named A-Suit, was developed to improve walking endurance in the lower limbs and reduce metabolic consumption. The method of ergonomics design was [...] Read more.
Concerning the biomechanics and energy consumption of the lower limbs, a soft exoskeleton for the powered plantar flexion of the ankle, named A-Suit, was developed to improve walking endurance in the lower limbs and reduce metabolic consumption. The method of ergonomics design was used based on the biological structures of the lower limbs. A profile of auxiliary forces was constructed according to the biological force of the Achilles tendon, and an iterative learning control was applied to shadow this auxiliary profile by iteratively modifying the traction displacements of drive units. During the evaluation of the performance experiments, four subjects wore the A-Suit and walked on a treadmill at different speeds and over different inclines. Average heart rate was taken as the evaluation index of metabolic consumption. When subjects walked at a moderate speed of 1.25 m/s, the average heart rate Hav under the Power-ON condition was 7.25 ± 1.32% (mean ± SEM) and 14.40 ± 2.63% less than the condition of No-suit and Power-OFF. Meanwhile, the additional mass of A-Suit led to a maximum Hav increase of 7.83 ± 1.44%. The overall reduction in Hav with Power-ON over the different inclines was 6.93 ± 1.84% and 13.4 ± 1.93% compared with that of the No-Suit and Power-OFF condition. This analysis offers interesting insights into the viability of using this technology for human augmentation and assistance for medical and other purposes. Full article
(This article belongs to the Special Issue Recent Advance in Medical and Rehabilitation Robots)
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