Progress and Challenges of Large-Scale Neural Recording
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 171
Special Issue Editors
Interests: epilepsy; brain regeneration; biohybrid systems; closed-loop neuroprostheses
Special Issues, Collections and Topics in MDPI journals
Interests: biophysical computational modeling; implantable neural interfaces
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The scientific community is witnessing the exponential growth of devices and tools to understand and decode the operating mode of the brain, and so inform the design of new therapeutic strategies for incurable brain disorders. The brain is a complex system whose function is contributed to by the coordinated activity of multiple specialized circuits made up by hundreds of neurons and non-neuronal cells. As such, studying its function requires a multi-scale approach, correlating single-cell activity with the function of micro-circuits and of brain networks as a whole.
Technologies for large-scale neural recording, such as high-density microelectrode arrays, have enabled a multi-scale approach to studying brain function, thanks to their exceptionally improved spatiotemporal resolution compared to standard techniques. Nonetheless, large-scale neural recording still presents with multiple and varied challenges, including distinguishing the signals contributed by single units, e.g., via spike sorting, handling of “big data”, which must rely on automated and computationally efficient algorithms. Additionally, challenges still remain in extracting information that would otherwise remain hidden within signals, e.g., through the deployment of machine learning and artificial intelligence.
In this Special Issue, we invite submissions addressing the challenges of large-scale neural recording aiming to advance the state-of-the-art and applications of currently available technologies.
Dr. Gabriella Panuccio
Dr. Erin Patrick
Guest Editors
Manuscript Submission Information
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Keywords
- neural recording
- high-density array probes
- feature extraction
- algorithm
- multi-scale approach
